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    ctnb-1 Beta-catenin-like protein 1 N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172214, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ctnb-1
    Official Full Name
    Beta-catenin-like protein 1 N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00019711
    Locus tag
    CELE_M01E11.2
    See related
    AllianceGenome:WB:WBGene00019711
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is expressed in head muscle; intestine; nerve ring; pharynx; and ventral nerve cord. Human ortholog(s) of this gene implicated in colorectal cancer; morbid obesity; and primary immunodeficiency disease. Orthologous to human CTNNBL1 (catenin beta like 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See ctnb-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003279.8 (5579666..5581993)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene RecQ-mediated genome instability protein 1 homolog Neighboring gene Kinesin motor domain-containing protein Neighboring gene Protein-S-isoprenylcysteine O-methyltransferase Neighboring gene Tensin homolog Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multiple ERK substrates execute single biological processes in Caenorhabditis elegans germ-line development. Arur S, et al. Proc Natl Acad Sci U S A, 2009 Mar 24. PMID 19264959, Free PMC Article
    2. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
    3. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Beta-catenin-like protein 1 N-terminal domain-containing protein
    NP_491634.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      5579666..5581993
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059233.6 → NP_491634.1  Beta-catenin-like protein 1 N-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491634.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      P91401
      Conserved Domains (1) summary
      pfam08216
      Location:43 → 144
      CTNNBL; Catenin-beta-like, Arm-motif containing nuclear
    Nucleotide Protein
    Heading Accession and Version

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