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    cdap-2 SH3 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 171906, updated on 9-Dec-2024

    Summary

    Official Symbol
    cdap-2
    Official Full Name
    SH3 domain-containing protein
    Primary source
    WormBase:WBGene00021549
    Locus tag
    CELE_Y44E3A.4
    See related
    AllianceGenome:WB:WBGene00021549
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in actin filament organization and cell migration. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis; focal segmental glomerulosclerosis 3; and immunodeficiency 61. Orthologous to several human genes including CD2AP (CD2 associated protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cdap-2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    9
    Sequence:
    Chromosome: I; NC_003279.8 (3318830..3330673, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Carboxylic ester hydrolase Neighboring gene Uncharacterized protein Neighboring gene Thioredoxin Neighboring gene Creatinase_N domain-containing protein;Hydrolase;Uncharacterized protein Neighboring gene FHA domain-containing protein Neighboring gene Hyphal_reg_CWP domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    SH3 domain-containing protein
    NP_491143.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3318830..3330673 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058742.6NP_491143.3  SH3 domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6A573
      Conserved Domains (1) summary
      cl17036
      Location:194249
      SH3; Src Homology 3 domain superfamily