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    nadk-2 NAD kinase 2, mitochondrial [ Caenorhabditis elegans ]

    Gene ID: 174846, updated on 9-Dec-2024

    Summary

    Official Symbol
    nadk-2
    Official Full Name
    NAD kinase 2, mitochondrial
    Primary source
    WormBase:WBGene00012463
    Locus tag
    CELE_Y17G7B.10
    See related
    AllianceGenome:WB:WBGene00012463
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable NAD+ kinase activity. Predicted to be involved in NAD metabolic process. Predicted to be active in mitochondrion. Orthologous to human NADK2 (NAD kinase 2, mitochondrial). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See nadk-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    9
    Sequence:
    Chromosome: II; NC_003280.10 (12049583..12059866)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Inositol-pentakisphosphate 2-kinase Neighboring gene Arrestin C-terminal-like domain-containing protein Neighboring gene Arrestin C-terminal-like domain-containing protein

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables NAD+ kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables NAD+ kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphotransferase activity, alcohol group as acceptor IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in NAD metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in NAD metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in NADP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    NAD kinase 2, mitochondrial
    NP_496565.2
    • Confirmed by transcript evidence
    NP_496566.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      12049583..12059866
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064164.7NP_496565.2  NAD kinase 2, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496565.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XXI6
      Conserved Domains (1) summary
      cl01255
      Location:71305
      DAGK_cat; Diacylglycerol kinase catalytic domain
    2. NM_064165.7NP_496566.1  NAD kinase 2, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496566.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XXI5
      Conserved Domains (1) summary
      cl01255
      Location:132366
      DAGK_cat; Diacylglycerol kinase catalytic domain