C16C10.4 putative histone deacetylase complex subunit SAP18 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: C16C10.4
Official Full Name: putative histone deacetylase complex subunit SAP18
Primary source: WormBase:WBGene00007625
Locus tag: CELE_C16C10.4
See related: AllianceGenome:WB:WBGene00007625
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including anal depressor muscle; hypodermis; nervous system; pharynx; and reproductive system. Orthologous to human SAP18 (Sin3A associated protein 18). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See C16C10.4 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 3

Sequence:: Chromosome: III; NC_003281.10 (4171336..4172223)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C16C10.5 (e-PCR)
- UniSTS:307257

C16C10.4 (e-PCR)
- UniSTS:320462

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables transcription corepressor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in negative regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: putative histone deacetylase complex subunit SAP18

NP_497833.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

4171336..4172223

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_065432.5 → NP_497833.1 putative histone deacetylase complex subunit SAP18 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_497833.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q09250

Conserved Domains (1) summary

pfam06487
Location:22 → 137

SAP18; Sin3 associated polypeptide p18 (SAP18)