U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ubxn-4 UBX domain-containing protein 4 [ Caenorhabditis elegans ]

    Gene ID: 176187, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ubxn-4
    Official Full Name
    UBX domain-containing protein 4
    Primary source
    WormBase:WBGene00022703
    Locus tag
    CELE_ZK353.8
    See related
    AllianceGenome:WB:WBGene00022703
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in ERAD pathway. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human UBXN4 (UBX domain protein 4). [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ubxn-4 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (8403718..8405422, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Leucine aminopeptidase 1 Neighboring gene Copper homeostasis protein cutC homolog Neighboring gene Cyclin-Y Neighboring gene PITH domain-containing protein ZK353.9

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Differential expression pattern of UBX family genes in Caenorhabditis elegans. Yamauchi S, et al. Biochem Biophys Res Commun, 2007 Jun 29. PMID 17498661
    2. RNA polymerase II CTD S2P is dispensable for embryogenesis but mediates exit from developmental diapause in C. elegans. Cassart C, et al. Sci Adv, 2020 Dec. PMID 33298437, Free PMC Article
    3. Caenorhabditis elegans UBX cofactors for CDC-48/p97 control spermatogenesis. Sasagawa Y, et al. Genes Cells, 2010 Dec. PMID 20977550
    4. Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. Lim PJ, et al. J Cell Biol, 2009 Oct 19. PMID 19822669, Free PMC Article
    5. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ERAD pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to unfolded protein IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    UBX domain-containing protein 4
    NP_001370812.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      8403718..8405422 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001382940.2 → NP_001370812.1  UBX domain-containing protein 4 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34631
      Conserved Domains (3) summary
      PRK05641
      Location:85 → 159
      PRK05641; putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated
      TIGR02794
      Location:167 → 252
      tolA_full; TolA protein
      cd16117
      Location:282 → 358
      UBX_UBXN4; Ubiquitin regulatory domain X (UBX) found in UBX domain protein 4 (UBXN4) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34631.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools