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    R09F10.1 Papain family cysteine protease [ Caenorhabditis elegans ]

    Gene ID: 181087, updated on 9-Dec-2024

    Summary

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    Official Symbol
    R09F10.1
    Official Full Name
    Papain family cysteine protease
    Primary source
    WormBase:WBGene00019986
    Locus tag
    CELE_R09F10.1
    See related
    AllianceGenome:WB:WBGene00019986
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in membrane. Predicted to be active in extracellular space and lysosome. Orthologous to human CTSW (cathepsin W). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See R09F10.1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    5
    Sequence:
    Chromosome: X; NC_003284.9 (8323592..8325192)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene ncRNA Neighboring gene Activated in Blocked Unfolded protein response Neighboring gene ncRNA Neighboring gene DOMON domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Cubilin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis involved in protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Papain family cysteine protease
    NP_509408.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      8323592..8325192
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077007.6 → NP_509408.1  Papain family cysteine protease [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509408.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23030
      Conserved Domains (2) summary
      pfam00112
      Location:169 → 381
      Peptidase_C1; Papain family cysteine protease
      pfam08246
      Location:82 → 138
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    Nucleotide Protein
    Heading Accession and Version

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