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    col-38 Cuticle collagen 38 [ Caenorhabditis elegans ]

    Gene ID: 174370, updated on 9-Dec-2024

    Summary

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    Official Symbol
    col-38
    Official Full Name
    Cuticle collagen 38
    Primary source
    WormBase:WBGene00000615
    Locus tag
    CELE_F54C9.4
    See related
    AllianceGenome:WB:WBGene00000615
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Involved in collagen and cuticulin-based cuticle development. Predicted to be located in nucleus. Is expressed in hyp7 syncytium and seam cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See col-38 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (8568035..8569088, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Ovule protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of C. elegans L4 cuticle collagen genes by the heterochronic protein LIN-29. Abete-Luzi P, et al. Genesis, 2018 May. PMID 29604168, Free PMC Article
    2. Use of an activated beta-catenin to identify Wnt pathway target genes in caenorhabditis elegans, including a subset of collagen genes expressed in late larval development. Jackson BM, et al. G3 (Bethesda), 2014 Apr 16. PMID 24569038, Free PMC Article
    3. Ketamine induces apical extracellular matrix modifications in Caenorhabditis elegans. Yücel D. Sci Rep, 2022 Dec 21. PMID 36543791, Free PMC Article
    4. New Roles for the Heterochronic Transcription Factor LIN-29 in Cuticle Maintenance and Lipid Metabolism at the Larval-to-Adult Transition in Caenorhabditis elegans. Abete-Luzi P, et al. Genetics, 2020 Mar. PMID 31974205, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in collagen and cuticulin-based cuticle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cuticle collagen 38
    NP_495810.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8568035..8569088 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063409.7 → NP_495810.1  Cuticle collagen 38 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495810.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q20754
      Conserved Domains (2) summary
      pfam01391
      Location:144 → 197
      Collagen; Collagen triple helix repeat (20 copies)
      smart01088
      Location:4 → 56
      Col_cuticle_N; Nematode cuticle collagen N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q20754.2

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