U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    gst-7 putative glutathione S-transferase 7 [ Caenorhabditis elegans ]

    Gene ID: 173842, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    gst-7
    Official Full Name
    putative glutathione S-transferase 7
    Primary source
    WormBase:WBGene00001755
    Locus tag
    CELE_F11G11.2
    See related
    AllianceGenome:WB:WBGene00001755
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable glutathione transferase activity. Involved in innate immune response. Is expressed in germ line; head; hypodermis; and intestine. Orthologous to human HPGDS (hematopoietic prostaglandin D synthase). [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See gst-7 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (4882062..4883358)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene arginine kinase Neighboring gene putative glutathione S-transferase 6 Neighboring gene putative glutathione S-transferase 8 Neighboring gene Serpentine Receptor, class E (Epsilon)

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Binding of hematin by a new class of glutathione transferase from the blood-feeding parasitic nematode Haemonchus contortus. van Rossum AJ, et al. Infect Immun, 2004 May. PMID 15102788, Free PMC Article
    2. Screening and analysis of Hc-ubq and Hc-gst related to desiccation survival of infective Haemonchus contortus larvae. Yang Y, et al. Vet Parasitol, 2015 Jun 15. PMID 25913452
    3. Heme transport and detoxification in nematodes: subproteomics evidence of differential role of glutathione transferases. Perally S, et al. J Proteome Res, 2008 Oct. PMID 18720983
    4. Structured Docosahexaenoic Acid (DHA) Enhances Motility and Promotes the Antioxidant Capacity of Aged C. elegans. Mora I, et al. Cells, 2023 Jul 26. PMID 37566010, Free PMC Article
    5. Arginine methylation of SKN-1 promotes oxidative stress resistance in Caenorhabditis elegans. Li H, et al. Redox Biol, 2019 Feb. PMID 30682707, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables glutathione transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glutathione transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in innate immune response HEP PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    putative glutathione S-transferase 7
    NP_494883.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      4882062..4883358
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062482.8 → NP_494883.1  putative glutathione S-transferase 7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494883.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P91253
      Conserved Domains (3) summary
      PTZ00057
      Location:8 → 201
      PTZ00057; glutathione s-transferase; Provisional
      cd03192
      Location:83 → 188
      GST_C_Sigma_like; C-terminal, alpha helical domain of Class Sigma-like Glutathione S-transferases
      cd03039
      Location:4 → 73
      GST_N_Sigma_like; GST_N family, Class Sigma_like; composed of GSTs belonging to class Sigma and similar proteins, including GSTs from class Mu, Pi and Alpha. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P91253.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools