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    ymel-1 ATP-dependent zinc metalloprotease YME1 homolog [ Caenorhabditis elegans ]

    Gene ID: 176460, updated on 27-Dec-2024

    Summary

    Official Symbol
    ymel-1
    Official Full Name
    ATP-dependent zinc metalloprotease YME1 homolog
    Primary source
    WormBase:WBGene00010842
    Locus tag
    CELE_M03C11.5
    See related
    AllianceGenome:WB:WBGene00010842
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metalloendopeptidase activity. Predicted to be involved in mitochondrial protein processing. Predicted to be located in mitochondrial inner membrane. Predicted to be part of m-AAA complex. Human ortholog(s) of this gene implicated in optic atrophy 11. Orthologous to human YME1L1 (YME1 like 1 ATPase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See ymel-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    9
    Sequence:
    Chromosome: III; NC_003281.10 (10416139..10421757)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ATP-dependent DNA helicase chl-1 Neighboring gene PH domain-containing protein Neighboring gene Histone acetyltransferase type B catalytic subunit Neighboring gene BBS2_C domain-containing protein Neighboring gene U4/U6 small nuclear ribonucleoprotein Prp3

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP-dependent peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metalloendopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial protein processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of m-AAA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ATP-dependent zinc metalloprotease YME1 homolog
    NP_001366715.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10416139..10421757
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001379892.2NP_001366715.1  ATP-dependent zinc metalloprotease YME1 homolog [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P54813
      Conserved Domains (1) summary
      TIGR01241
      Location:195685
      FtsH_fam; ATP-dependent metalloprotease FtsH