U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    F27C1.11 Doublecortin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 3565116, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    F27C1.11
    Official Full Name
    Doublecortin domain-containing protein
    Primary source
    WormBase:WBGene00017858
    Locus tag
    CELE_F27C1.11
    See related
    AllianceGenome:WB:WBGene00017858
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in intracellular signal transduction. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy; autosomal recessive nonsyndromic deafness 77; and orofacial cleft. Orthologous to human LOXHD1 (lipoxygenase homology PLAT domains 1). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See F27C1.11 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    28
    Sequence:
    Chromosome: I; NC_003279.8 (5433905..5443026, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Cuticle collagen dpy-5 Neighboring gene Ovule protein Neighboring gene Doublecortin domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Doublecortin domain-containing protein
    NP_001362169.1
    • Confirmed by transcript evidence
    NP_001362170.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      5433905..5443026 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001374895.3 → NP_001362170.1  Doublecortin domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5K1IAB7
      Conserved Domains (4) summary
      cd00113
      Location:713 → 823
      PLAT; PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and ...
      cd01617
      Location:26 → 94
      DCX; Dublecortin-like domain structurally similar to a beta-grasp ubiquitin-like fold
      pfam11179
      Location:89 → 407
      DUF2967; Protein of unknown function (DUF2967)
      cl00011
      Location:564 → 684
      PLAT; PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and ...

    2. NM_001374894.3 → NP_001362169.1  Doublecortin domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5K1IBA0
      Conserved Domains (4) summary
      cd00113
      Location:713 → 823
      PLAT; PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and ...
      PTZ00112
      Location:95 → 410
      PTZ00112; origin recognition complex 1 protein; Provisional
      cd01617
      Location:26 → 94
      DCX; Dublecortin-like domain structurally similar to a beta-grasp ubiquitin-like fold
      cl00011
      Location:564 → 684
      PLAT; PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and ...
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools