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    Y73E7A.1 Coiled-coil domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 171725, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y73E7A.1
    Official Full Name
    Coiled-coil domain-containing protein
    Primary source
    WormBase:WBGene00022268
    Locus tag
    CELE_Y73E7A.1
    See related
    AllianceGenome:WB:WBGene00022268
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transcription coactivator activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in midbody. Predicted to be active in nucleus. Orthologous to human CCDC124 (coiled-coil domain containing 124). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y73E7A.1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (1629003..1633498)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Bladder cancer-associated protein Neighboring gene WD and tetratricopeptide repeats protein 1;WD_REPEATS_REGION domain-containing protein Neighboring gene Beta-1,4-N-acetylgalactosaminyltransferase bre-4 Neighboring gene Mucin-5AC Neighboring gene Semaphorin-2A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Coiled-coil domain-containing protein
    NP_001040712.1
    • Confirmed by transcript evidence
    NP_001040713.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      1629003..1633498
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047247.4 → NP_001040712.1  Coiled-coil domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040712.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9GUM1
      Conserved Domains (1) summary
      pfam06244
      Location:96 → 215
      DUF1014; Protein of unknown function (DUF1014)

    2. NM_001047248.4 → NP_001040713.1  Coiled-coil domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040713.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2AAB8
      Conserved Domains (1) summary
      pfam06244
      Location:19 → 138
      DUF1014; Protein of unknown function (DUF1014)
    Nucleotide Protein
    Heading Accession and Version

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