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    tun tungus [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36743, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tunprovided by FlyBase
    Official Full Name
    tungusprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034046
    Locus tag
    Dmel_CG8253
    See related
    AllianceGenome:FB:FBgn0034046
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD38553; CG8253; Dmel\CG8253; Ntaq1
    Summary
    Predicted to enable protein-N-terminal glutamine amidohydrolase activity. Predicted to be active in cytosol and nucleus. Is expressed in organism. Orthologous to human NTAQ1 (N-terminal glutamine amidase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See tun in Genome Data Viewer
    Location:
    52C5-52C8; 2-75 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (15794000..15855645)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (11681505..11743150)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Z band alternatively spliced PDZ-motif protein 52 Neighboring gene uncharacterized protein Neighboring gene Pox neuro Neighboring gene uncharacterized protein Neighboring gene cGAS-like receptor 1 Neighboring gene Glycerophosphate oxidase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Glutamine-specific N-terminal amidase, a component of the N-end rule pathway. Wang H, et al. Mol Cell, 2009 Jun 26. PMID 19560421, Free PMC Article
    2. The Drosophila Pox neuro gene: control of male courtship behavior and fertility as revealed by a complete dissection of all enhancers. Boll W, et al. Development, 2002 Dec. PMID 12421707
    3. dRTEL1 is essential for the maintenance of Drosophila male germline stem cells. Yang Y, et al. PLoS Genet, 2021 Oct. PMID 34644293, Free PMC Article
    4. Shared visual attention and memory systems in the Drosophila brain. van Swinderen B, et al. PLoS One, 2009 Jun 19. PMID 19543525, Free PMC Article
    5. A high-fat diet impacts memory and gene expression of the head in mated female Drosophila melanogaster. Rivera O, et al. J Comp Physiol B, 2019 Apr. PMID 30810797, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein-N-terminal asparagine amidohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-N-terminal glutamine amidohydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-N-terminal glutamine amidohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tungus
    Names
    CG8253-PA
    CG8253-PB
    CG8253-PC
    CG8253-PD
    tun-PA
    tun-PB
    tun-PC
    tun-PD
    NP_001246351.1
    NP_001246352.1
    NP_001286468.1
    NP_611061.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      15794000..15855645
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299539.1 → NP_001286468.1  tungus, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286468.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7K2Y9
      UniProtKB/TrEMBL
      A0A0B4K882
      Conserved Domains (1) summary
      pfam09764
      Location:15 → 185
      Nt_Gln_amidase; N-terminal glutamine amidase

    2. NM_001259422.2 → NP_001246351.1  tungus, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246351.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7K2Y9
      UniProtKB/TrEMBL
      A0A0B4K882
      Conserved Domains (1) summary
      pfam09764
      Location:15 → 185
      Nt_Gln_amidase; N-terminal glutamine amidase

    3. NM_001259423.2 → NP_001246352.1  tungus, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246352.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7K2Y9
      UniProtKB/TrEMBL
      A0A0B4K882
      Conserved Domains (1) summary
      pfam09764
      Location:15 → 185
      Nt_Gln_amidase; N-terminal glutamine amidase

    4. NM_137217.3 → NP_611061.1  tungus, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611061.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7K2Y9
      UniProtKB/TrEMBL
      A0A0B4K882
      Related
      FBpp0086423
      Conserved Domains (1) summary
      pfam09764
      Location:15 → 185
      Nt_Gln_amidase; N-terminal glutamine amidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K882 A0A0B4K882
    Q7K2Y9.1 Q7K2Y9
    Q95SZ1 Q95SZ1

    Gene LinkOut

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