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    CG15818 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34019, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15818provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031910
    Locus tag
    Dmel_CG15818
    See related
    AllianceGenome:FB:FBgn0031910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15818
    Summary
    Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to be located in extracellular region. Predicted to be active in external side of plasma membrane. Is expressed in embryonic proventriculus and embryonic/larval midgut. Human ortholog(s) of this gene implicated in 3MC syndrome 3; asthma; lung disease (multiple); respiratory syncytial virus infectious disease; and rhinitis. Orthologous to several human genes including COLEC10 (collectin subfamily member 10); SFTPA1 (surfactant protein A1); and SFTPA2 (surfactant protein A2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15818 in Genome Data Viewer
    Location:
    27F3-27F3; 2-26 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7410909..7412229)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7410909..7412229)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46205 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene chameau Neighboring gene long non-coding RNA:CR43857 Neighboring gene mir-275 stem loop

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An endogenous Drosophila receptor for glycans bearing alpha 1,3-linked core fucose residues. Bouyain S, et al. J Biol Chem, 2002 Jun 21. PMID 11960993
    2. Evidence of spatially varying selection acting on four chromatin-remodeling loci in Drosophila melanogaster. Levine MT, et al. Genetics, 2008 May. PMID 18245821, Free PMC Article
    3. A genome-wide scan for genes under balancing selection in Drosophila melanogaster. Croze M, et al. BMC Evol Biol, 2017 Jan 13. PMID 28086750, Free PMC Article
    4. Molecular evolution and population genetics of duplicated accessory gland protein genes in Drosophila. Holloway AK, et al. Mol Biol Evol, 2004 Sep. PMID 15215320
    5. High fat diet induces sex-specific differential gene expression in Drosophila melanogaster. Stobdan T, et al. PLoS One, 2019. PMID 30861021, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables pattern recognition receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15818-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      7410909..7412229
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135272.4 → NP_609116.1  uncharacterized protein Dmel_CG15818 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609116.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VM16
      Related
      FBpp0079070
      Conserved Domains (1) summary
      cd00037
      Location:164 → 278
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VM16 Q9VM16

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