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    ATR2 Atr2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855322, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ATR2
    Official Full Name
    Atr2p
    Primary source
    SGD:S000004892
    Locus tag
    YMR279C
    See related
    AllianceGenome:SGD:S000004892; FungiDB:YMR279C; VEuPathDB:YMR279C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable borate efflux transmembrane transporter activity. Involved in borate transmembrane transport. Located in cell periphery. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ATR2 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (824729..826351, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene protein serine/threonine phosphatase Neighboring gene phosphoribomutase PRM15 Neighboring gene DNA-binding transcription factor CAT8 Neighboring gene N-acetylglucosaminylphosphatidylinositol deacetylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Roles of ATR1 paralogs YMR279c and YOR378w in boron stress tolerance. Bozdag GO, et al. Biochem Biophys Res Commun, 2011 Jun 17. PMID 21621519
    2. Identification of a novel system for boron transport: Atr1 is a main boron exporter in yeast. Kaya A, et al. Mol Cell Biol, 2009 Jul. PMID 19414602, Free PMC Article
    3. Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae. Sakaki K, et al. J Biochem, 2003 Sep. PMID 14561723
    4. A Protein-Protein Interaction Analysis Suggests a Wide Range of New Functions for the p21-Activated Kinase (PAK) Ste20. Joshua IM, et al. Int J Mol Sci, 2023 Nov 2. PMID 37958899, Free PMC Article
    5. Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae. Kyriakou D, et al. BMC Biol, 2016 Dec 7. PMID 27927215, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables borate efflux transmembrane transporter activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in borate transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Atr2p
    NP_014006.1
    • Putative boron transporter involved in boron efflux and resistance; overexpression mutant but not null mutant displays boron tolerance phenotype; identified as a heat-induced gene in a high-throughout screen; YMR279C is not an essential gene; YMR279C has a paralog, ATR1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      824729..826351 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182786.1 → NP_014006.1  TPA: Atr2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014006.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0A6, Q03263
      UniProtKB/TrEMBL
      A6ZMZ5, B3LMG7, B5VQ46, C7GTM0, C8ZFE6, G2WKY8, N1NZ59
      Conserved Domains (1) summary
      cd17476
      Location:74 → 519
      MFS_Amf1_MDR_like; Saccharomyces cerevisiae low affinity ammonium transporter Amf1p/YOR378W, aminotriazole resistance protein Atr1p, and similar transporters of the Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03263.1

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