R05D11.9 Sphingomyelin phosphodiesterase 4 [Caenorhabditis elegans] - Gene

Summary

Official Symbol: R05D11.9
Official Full Name: Sphingomyelin phosphodiesterase 4
Primary source: WormBase:WBGene00011037
Locus tag: CELE_R05D11.9
See related: AllianceGenome:WB:WBGene00011037
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable sphingomyelin phosphodiesterase D activity. Predicted to be involved in ceramide biosynthetic process; glycerophospholipid catabolic process; and sphingomyelin catabolic process. Predicted to be located in endoplasmic reticulum and trans-Golgi network. Orthologous to human SMPD4 (sphingomyelin phosphodiesterase 4). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

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Function	Evidence Code	Pubs
enables sphingomyelin phosphodiesterase D activity	IBA Inferred from Biological aspect of Ancestor more info
enables sphingomyelin phosphodiesterase D activity	IEA Inferred from Electronic Annotation more info
enables sphingomyelin phosphodiesterase D activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in ceramide biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in glycerophospholipid catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in sphingomyelin catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in sphingomyelin catabolic process	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in endoplasmic reticulum	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in trans-Golgi network	ISS Inferred from Sequence or Structural Similarity more info	PubMed

NP_492324.2

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