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    wdr-31 WD_REPEATS_REGION domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173617, updated on 9-Dec-2024

    Summary

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    Official Symbol
    wdr-31
    Official Full Name
    WD_REPEATS_REGION domain-containing protein
    Primary source
    WormBase:WBGene00020231
    Locus tag
    CELE_T05A8.5
    See related
    AllianceGenome:WB:WBGene00020231
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in ciliated neurons. Orthologous to human WDR31 (WD repeat domain 31). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See wdr-31 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (2731105..2735292, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Neuropeptide-Like Protein Neighboring gene Neprilysin-2 Neighboring gene Uncharacterized protein Neighboring gene tRNA-Leu Neighboring gene ncRNA Neighboring gene tRNA-Leu Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. WDR31 displays functional redundancy with GTPase-activating proteins (GAPs) ELMOD and RP2 in regulating IFT complex and recruiting the BBSome to cilium. Cevik S, et al. Life Sci Alliance, 2023 Aug. PMID 37208194, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    WD_REPEATS_REGION domain-containing protein
    NP_494344.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      2731105..2735292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061943.5 → NP_494344.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494344.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44856
      Conserved Domains (2) summary
      sd00039
      Location:147 → 182
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:54 → 301
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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