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    D1007.8 Nucleic acid-binding, OB-fold protein [ Caenorhabditis elegans ]

    Gene ID: 172066, updated on 9-Dec-2024

    Summary

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    Official Symbol
    D1007.8
    Official Full Name
    Nucleic acid-binding, OB-fold protein
    Primary source
    WormBase:WBGene00017005
    Locus tag
    CELE_D1007.8
    See related
    AllianceGenome:WB:WBGene00017005
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable single-stranded DNA binding activity and telomeric DNA binding activity. Predicted to be involved in DNA replication; double-strand break repair via homologous recombination; and nucleotide-excision repair. Predicted to be part of DNA replication factor A complex. Predicted to be active in chromosome, telomeric region and site of double-strand break. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See D1007.8 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (4604403..4605380)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene CID domain-containing protein Neighboring gene Ell-associated factor Eaf Neighboring gene NudC domain-containing protein 1 Neighboring gene UBR-type domain-containing protein Neighboring gene ncRNA Neighboring gene Lupus La protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans. Suen KM, et al. Nat Commun, 2020 Aug 25. PMID 32843637, Free PMC Article
    2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables single-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables telomeric DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in double-strand break repair via homologous recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nucleotide-excision repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of DNA replication factor A complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in chromosome, telomeric region IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in site of double-strand break IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Nucleic acid-binding, OB-fold protein
    NP_491405.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4604403..4605380
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059004.6 → NP_491405.2  Nucleic acid-binding, OB-fold protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491405.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9TXQ8
    Nucleotide Protein
    Heading Accession and Version

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