U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    pck-3 phosphoenolpyruvate carboxykinase (GTP) [ Caenorhabditis elegans ]

    Gene ID: 177360, updated on 14-Nov-2024

    Summary

    Official Symbol
    pck-3
    Official Full Name
    phosphoenolpyruvate carboxykinase (GTP)
    Primary source
    WormBase:WBGene00019151
    Locus tag
    CELE_H04M03.1
    See related
    AllianceGenome:WB:WBGene00019151
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including carboxylic acid metabolic process; cellular response to dexamethasone stimulus; and gluconeogenesis. Predicted to be active in cytosol. Is expressed in excretory cell. [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See pck-3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    7
    Sequence:
    Chromosome: IV; NC_003282.8 (5896641..5899112)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Nematode Specific Peptide family, group B Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ras-associating domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables carboxy-lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables manganese ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphoenolpyruvate carboxykinase (GTP) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphoenolpyruvate carboxykinase (GTP) activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphoenolpyruvate carboxykinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables purine nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to glucose stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in gluconeogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in gluconeogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glycerol biosynthetic process from pyruvate IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in oxaloacetate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in propionate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in response to lipid IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in response to starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    phosphoenolpyruvate carboxykinase (GTP)
    NP_500887.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      5896641..5899112
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068486.5NP_500887.1  phosphoenolpyruvate carboxykinase (GTP) [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500887.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9TYQ8
      Conserved Domains (1) summary
      cl22860
      Location:60624
      PEPCK_HprK; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...