U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    bcl-7 BCL7-like protein [ Caenorhabditis elegans ]

    Gene ID: 175838, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    bcl-7
    Official Full Name
    BCL7-like protein
    Primary source
    WormBase:WBGene00016192
    Locus tag
    CELE_C28H8.1
    See related
    AllianceGenome:WB:WBGene00016192
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in Wnt signaling pathway; apoptotic process; and cell differentiation. Predicted to be located in nucleus. Is expressed in distal tip cell; germ cell; gonadal sheath cell; and hypodermis. Orthologous to several human genes including BCL7A (BAF chromatin remodeling complex subunit BCL7A). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See bcl-7 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003281.10 (5926086..5926987)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Tryptophan 2,3-dioxygenase Neighboring gene Uncharacterized protein Neighboring gene putative dynactin subunit 2 Neighboring gene Matrix metalloproteinase-A Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ovule protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The Tumor Suppressor BCL7B Functions in the Wnt Signaling Pathway. Uehara T, et al. PLoS Genet, 2015 Jan. PMID 25569233, Free PMC Article
    2. Multiple ERK substrates execute single biological processes in Caenorhabditis elegans germ-line development. Arur S, et al. Proc Natl Acad Sci U S A, 2009 Mar 24. PMID 19264959, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    BCL7-like protein
    NP_498287.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      5926086..5926987
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065886.6 → NP_498287.1  BCL7-like protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498287.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09242
      Conserved Domains (1) summary
      pfam04714
      Location:5 → 52
      BCL_N; BCL7, N-terminal conserver region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09242.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools