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    CG13077 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35252, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13077provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032810
    Locus tag
    Dmel_CG13077
    See related
    AllianceGenome:FB:FBgn0032810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13077
    Summary
    Predicted to enable heme binding activity and transmembrane ascorbate ferrireductase activity. Is expressed in adult head and photoreceptor neurons. Orthologous to several human genes including CYB561D2 (cytochrome b561 family member D2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13077 in Genome Data Viewer
    Location:
    37F1-37F2; 2-54 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19565863..19567359)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19565863..19567359)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Thioester-containing protein 5 pseudogene Neighboring gene uncharacterized protein Neighboring gene spitz Neighboring gene mir-2a-2 stem loop Neighboring gene mir-2a-1 stem loop

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparison of insect and human cytochrome b561 proteins: Insights into candidate ferric reductases in insects. Holst JD, et al. PLoS One, 2023. PMID 38039324, Free PMC Article
    2. CULD is required for rhodopsin and TRPL channel endocytic trafficking and survival of photoreceptor cells. Xu Y, et al. J Cell Sci, 2016 Jan 15. PMID 26598556, Free PMC Article
    3. Evolutionary rate covariation identifies new members of a protein network required for Drosophila melanogaster female post-mating responses. Findlay GD, et al. PLoS Genet, 2014 Jan. PMID 24453993, Free PMC Article
    4. Iap2 is required for a sustained response in the Drosophila Imd pathway. Valanne S, et al. Dev Comp Immunol, 2007. PMID 17343912
    5. Age-Related Changes of Gene Expression Profiles in Drosophila. Bordet G, et al. Genes (Basel), 2021 Dec 14. PMID 34946931, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane ascorbate ferrireductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transmembrane monodehydroascorbate reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13077-PA
    CG13077-PB
    NP_001260592.1
    NP_609990.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      19565863..19567359
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136146.3 → NP_609990.1  uncharacterized protein Dmel_CG13077, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609990.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIT5
      Related
      FBpp0080798
      Conserved Domains (1) summary
      pfam03188
      Location:94 → 228
      Cytochrom_B561; Eukaryotic cytochrome b561

    2. NM_001273663.1 → NP_001260592.1  uncharacterized protein Dmel_CG13077, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260592.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PG89
      Conserved Domains (1) summary
      pfam03188
      Location:51 → 185
      Cytochrom_B561; Eukaryotic cytochrome b561
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PG89 M9PG89
    Q9VIT5 Q9VIT5

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