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    CG7945 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39679, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7945provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036505
    Locus tag
    Dmel_CG7945
    See related
    AllianceGenome:FB:FBgn0036505
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BAG2; CG17014; Dmel\CG7945
    Summary
    Predicted to enable adenyl-nucleotide exchange factor activity. Predicted to be involved in protein stabilization. Is expressed in organism. Orthologous to human BAG2 (BAG cochaperone 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7945 in Genome Data Viewer
    Location:
    71D4-71D4; 3-43 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15521711..15524137, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15514811..15517237, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene midgut expression 1 Neighboring gene antisense RNA:CR43159 Neighboring gene yellow-k Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Myeloid Leukemia Factor Acts in a Chaperone Complex to Regulate Transcription Factor Stability and Gene Expression. Dyer JO, et al. J Mol Biol, 2017 Jun 30. PMID 27984043, Free PMC Article
    2. Recent and recurrent selective sweeps of the antiviral RNAi gene Argonaute-2 in three species of Drosophila. Obbard DJ, et al. Mol Biol Evol, 2011 Feb. PMID 20978039, Free PMC Article
    3. EDEM Function in ERAD Protects against Chronic ER Proteinopathy and Age-Related Physiological Decline in Drosophila. Sekiya M, et al. Dev Cell, 2017 Jun 19. PMID 28633019, Free PMC Article
    4. Thermoprotection of synaptic transmission in a Drosophila heat shock factor mutant is accompanied by increased expression of Hsp83 and DnaJ-1. Neal SJ, et al. Physiol Genomics, 2006 May 16. PMID 16595740
    5. Genomic analysis of heat-shock factor targets in Drosophila. Birch-Machin I, et al. Genome Biol, 2005. PMID 15998452, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables adenyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables adenyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-folding chaperone binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein stabilization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7945-PA
    CG7945-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      15521711..15524137 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168624.3 → NP_730051.1  uncharacterized protein Dmel_CG7945, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730051.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95RY2
      Related
      FBpp0075353

    2. NM_140516.3 → NP_648773.1  uncharacterized protein Dmel_CG7945, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648773.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VUP9, Q9VUQ0, Q9VUQ1, Q9VUQ2
      Related
      FBpp0075352
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MQK5 Q8MQK5
    Q95RY2 Q95RY2
    Q9VUQ1 Q9VUQ1

    Gene LinkOut

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