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    ebo ellipsoid body open [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 47141, updated on 9-Dec-2024

    Summary

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    Official Symbol
    eboprovided by FlyBase
    Official Full Name
    ellipsoid body openprovided by FlyBase
    Primary source
    FLYBASE:FBgn0266572
    Locus tag
    Dmel_CG3923
    See related
    AllianceGenome:FB:FBgn0266572
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3923; Dmel\CG3923; EBO; EG:165H7.3; Exp1; exp6; Exp6
    Summary
    Predicted to enable nuclear export signal receptor activity and small GTPase binding activity. Involved in brain development; flight behavior; and short-term memory. Orthologous to human XPO6 (exportin 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ebo in Genome Data Viewer
    Location:
    1B4-1B4; 1-0 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (471019..476579, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (365052..370612, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 4g1 Neighboring gene asense Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The central complex of Drosophila melanogaster is involved in flight control: studies on mutants and mosaics of the gene ellipsoid body open. Ilius M, et al. J Neurogenet, 1994 Jul. PMID 7965387
    2. The central complex of Drosophila melanogaster is involved in flight control: studies on mutants and mosaics of the gene ellipsoid body open. Ilius M, et al. J Neurogenet, 2007 Oct-Dec. PMID 18161592
    3. Prostaglandins limit nuclear actin to control nucleolar function during oogenesis. Talbot DE, et al. Front Cell Dev Biol, 2023. PMID 36875757, Free PMC Article
    4. Mushroom bodies modulate salience-based selective fixation behavior in Drosophila. Xi W, et al. Eur J Neurosci, 2008 Mar. PMID 18364023
    5. Analysis of a spatial orientation memory in Drosophila. Neuser K, et al. Nature, 2008 Jun 26. PMID 18509336

    See all (59) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables nuclear export signal receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in adult walking behavior TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in central complex development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in flight behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mushroom body development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein export from nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in short-term memory IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ellipsoid body open
    Names
    CG3923-PA
    CG3923-PB
    CG3923-PC
    Exportin-6
    ebo-PA
    ebo-PB
    ebo-PC
    ellipsoid-body-open
    exportin 6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      471019..476579 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080140.3 → NP_524879.2  ellipsoid body open, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524879.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T9F5, Q9W5G1
      Related
      FBpp0070093
      Conserved Domains (2) summary
      pfam03810
      Location:30 → 98
      IBN_N; Importin-beta N-terminal domain
      pfam08389
      Location:110 → 259
      Xpo1; Exportin 1-like protein

    2. NM_001297810.1 → NP_001284739.1  ellipsoid body open, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284739.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T9F5, X2J9Y4
      Conserved Domains (2) summary
      pfam03810
      Location:30 → 98
      IBN_N; Importin-beta N-terminal domain
      pfam08389
      Location:110 → 259
      Xpo1; Exportin 1-like protein

    3. NM_001297809.1 → NP_001284738.1  ellipsoid body open, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284738.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T9F5, X2JDN0
      Conserved Domains (2) summary
      pfam03810
      Location:30 → 98
      IBN_N; Importin-beta N-terminal domain
      pfam08389
      Location:110 → 259
      Xpo1; Exportin 1-like protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O46055 O46055
    Q8T9F5 Q8T9F5
    Q9W5G1 Q9W5G1
    X2J9Y4 X2J9Y4
    X2JDN0 X2JDN0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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