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    Cyp28a5 Cytochrome P450 28a5 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34817, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cyp28a5provided by FlyBase
    Official Full Name
    Cytochrome P450 28a5provided by FlyBase
    Primary source
    FLYBASE:FBgn0028940
    Locus tag
    Dmel_CG8864
    See related
    AllianceGenome:FB:FBgn0028940
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    28a5; BEST:GH10483; BG:DS00180.11; CG8864; cyp28a5; Cyp28A5; CYP28a5; CYP28A5; Dmel\CG8864; DS00180.11; gh10483
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in several structures, including adult head; embryonic small intestine; embryonic/larval midgut; embryonic/larval tracheal section; and small intestine primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cyp28a5 in Genome Data Viewer
    Location:
    34E5-34E5; 2-50 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13977302..13979569)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13977302..13979569)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Nimrod B5 Neighboring gene Nimrod C1 Neighboring gene Hemese Neighboring gene Nimrod C2 Neighboring gene rickets Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GeneID in Drosophila. Parra G, et al. Genome Res, 2000 Apr. PMID 10779490, Free PMC Article
    2. Gene Regulatory Variation in Drosophila melanogaster Renal Tissue. Glaser-Schmitt A, et al. Genetics, 2018 Sep. PMID 29976765, Free PMC Article
    3. The involvement of cytochrome P450 monooxygenases in methanol elimination in Drosophila melanogaster larvae. Wang SP, et al. Arch Insect Biochem Physiol, 2012 Apr. PMID 22508581
    4. Association of detoxification enzymes with butene-fipronil in larvae and adults of Drosophila melanogaster. Arain MS, et al. Environ Sci Pollut Res Int, 2018 Apr. PMID 29380196
    5. Identification and characterization of CYPs induced in the Drosophila antenna by exposure to a plant odorant. Baldwin SR, et al. Sci Rep, 2021 Oct 15. PMID 34654888, Free PMC Article

    See all (51) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450 28a5
    Names
    CG8864-PA
    Cyp28a5-PA
    cytochrome P450
    NP_609694.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      13977302..13979569
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135850.3 → NP_609694.1  cytochrome P450 28a5 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609694.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V419
      Related
      FBpp0080164
      Conserved Domains (1) summary
      cl12078
      Location:33 → 500
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V419.1 Q9V419

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