U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Cyp9f2 Cytochrome P450 9f2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41520, updated on 12-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Cyp9f2provided by FlyBase
    Official Full Name
    Cytochrome P450 9f2provided by FlyBase
    Primary source
    FLYBASE:FBgn0038037
    Locus tag
    Dmel_CG11466
    See related
    AllianceGenome:FB:FBgn0038037
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    9f2; anon-EST:Posey150; CG11466; Cyp 9f2; Cyp9F2; CYP9F2; Dmel\CG11466
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Involved in wing disc development. Is expressed in adult head; adult heart; embryonic/larval midgut; epithelium; and yolk nucleus. Human ortholog(s) of this gene implicated in Ghosal hematodiaphyseal syndrome; cerebral infarction; essential hypertension; familial Mediterranean fever; and leukemia (multiple). Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A4 (cytochrome P450 family 3 subfamily A member 4); and CYP3A43 (cytochrome P450 family 3 subfamily A member 43). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Cyp9f2 in Genome Data Viewer
    Location:
    87B9-87B9; 3-52 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12403340..12406028, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8229062..8231750, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Sol1 Neighboring gene Cytochrome P450 9f3 Neighboring gene DNA ligase 3 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Dibutyl Phthalate Exposure Disrupts Evolutionarily Conserved Insulin and Glucagon-Like Signaling in Drosophila Males. Williams MJ, et al. Endocrinology, 2016 Jun. PMID 27100621
    2. RNA interference validation of detoxification genes involved in ivermectin tolerance in Drosophila melanogaster. Kim JH, et al. Insect Mol Biol, 2018 Oct. PMID 29888824
    3. The involvement of cytochrome P450 monooxygenases in methanol elimination in Drosophila melanogaster larvae. Wang SP, et al. Arch Insect Biochem Physiol, 2012 Apr. PMID 22508581
    4. Hazardous effects of octopamine receptor agonists on altering metabolism-related genes and behavior of Drosophila melanogaster. Ahmed MAI, et al. Chemosphere, 2020 Aug. PMID 32283422, Free PMC Article
    5. Association of detoxification enzymes with butene-fipronil in larvae and adults of Drosophila melanogaster. Arain MS, et al. Environ Sci Pollut Res Int, 2018 Apr. PMID 29380196

    See all (66) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in wing disc development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    cytochrome P450 9f2
    Names
    CG11466-PA
    Cyp9f2-PA
    cytochrome P450
    NP_650189.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12403340..12406028 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141932.3 → NP_650189.1  cytochrome P450 9f2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650189.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VG82
      Related
      FBpp0082070
      Conserved Domains (1) summary
      pfam00067
      Location:36 → 510
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VG82.1 Q9VG82

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools