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    CG10516 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39738, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10516provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036549
    Locus tag
    Dmel_CG10516
    See related
    AllianceGenome:FB:FBgn0036549
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10516
    Summary
    Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human SPSB3 (splA/ryanodine receptor domain and SOCS box containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10516 in Genome Data Viewer
    Location:
    72C1-72C1; 3-43 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15968204..15969902)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15961304..15963002)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Brr2 U5 snRNP complex subunit Neighboring gene brahma Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The guanine exchange factor Gartenzwerg and the small GTPase Arl1 function in the same pathway with Arfaptin during synapse growth. Chang L, et al. Biol Open, 2015 Jun 26. PMID 26116655, Free PMC Article
    2. Forcing contacts between mitochondria and the endoplasmic reticulum extends lifespan in a Drosophila model of Alzheimer's disease. Garrido-Maraver J, et al. Biol Open, 2020 Jan 14. PMID 31822473, Free PMC Article
    3. Molecular genetic analyses of polytene chromosome region 72A-D in Drosophila melanogaster reveal a gene desert in 72D. Cooper MT, et al. PLoS One, 2011. PMID 21853143, Free PMC Article
    4. Photoperiod-Dependent Expression of MicroRNA in Drosophila. Pegoraro M, et al. Int J Mol Sci, 2022 Apr 29. PMID 35563325, Free PMC Article
    5. Crtc modulates fasting programs associated with 1-C metabolism and inhibition of insulin signaling. Wang T, et al. Proc Natl Acad Sci U S A, 2021 Mar 23. PMID 33723074, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10516-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      15968204..15969902
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140562.2 → NP_648819.2  uncharacterized protein Dmel_CG10516 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648819.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VUW0
      Related
      FBpp0075267
      Conserved Domains (1) summary
      cd12876
      Location:51 → 233
      SPRY_SOCS3; SPRY domain in the suppressor of cytokine signaling 3 (SOCS3) family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VUW0 Q9VUW0

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