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    CG18599 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42191, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG18599provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038592
    Locus tag
    Dmel_CG18599
    See related
    AllianceGenome:FB:FBgn0038592
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG18599
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in central nervous system development; neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including CNS glial cell; cuboidal/columnar epithelium; ganglia; larval nervous system; and mushroom body primordium. Orthologous to human NOTO (notochord homeobox). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG18599 in Genome Data Viewer
    Location:
    90F11-91A1; 3-63 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18267789..18271172)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14093511..14096894)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene RNA polymerase II subunit D Neighboring gene transcriptional Adaptor 2a Neighboring gene Trimethylguanosine synthase 1 Neighboring gene modigliani Neighboring gene Vacuolar protein sorting 39 Neighboring gene eukaryotic translation initiation factor 1A Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in central nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in neuron differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG18599-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18267789..18271172
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142444.2NP_650701.1  uncharacterized protein Dmel_CG18599 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650701.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VEA3
      Related
      FBpp0082993
      Conserved Domains (1) summary
      pfam00046
      Location:320372
      Homeobox; Homeobox domain