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    JMJD7 Jumonji domain containing 7 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39514, updated on 17-Dec-2024

    Summary

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    Official Symbol
    JMJD7provided by FlyBase
    Official Full Name
    Jumonji domain containing 7provided by FlyBase
    Primary source
    FLYBASE:FBgn0036366
    Locus tag
    Dmel_CG10133
    See related
    AllianceGenome:FB:FBgn0036366
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10133; Dmel\CG10133
    Summary
    Predicted to enable endopeptidase activity and peptidyl-lysine 3-dioxygenase activity. Located in cytoplasm. Is expressed in organism. Used to study alcohol use disorder. Orthologous to human JMJD7 (jumonji domain containing 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See JMJD7 in Genome Data Viewer
    Location:
    70B1-70B1; 3-40 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (13449187..13450283, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (13442287..13443383, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene combover Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans. Chowdhury R, et al. Sci Rep, 2022 Apr 11. PMID 35410347, Free PMC Article
    2. JmjC domain proteins modulate circadian behaviors and sleep in Drosophila. Shalaby NA, et al. Sci Rep, 2018 Jan 16. PMID 29339751, Free PMC Article
    3. Alcohol-Induced Behaviors Require a Subset of Drosophila JmjC-Domain Histone Demethylases in the Nervous System. Pinzón JH, et al. Alcohol Clin Exp Res, 2017 Dec. PMID 28940624, Free PMC Article
    4. Use of a Drosophila model to identify genes regulating Plasmodium growth in the mosquito. Brandt SM, et al. Genetics, 2008 Nov. PMID 18791251, Free PMC Article
    5. Drosophila spermatid individualization is sensitive to temperature and fatty acid metabolism. Ben-David G, et al. Spermatogenesis, 2015 Jan-Apr. PMID 26413411, Free PMC Article

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 2-oxoglutarate-dependent dioxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptidyl-lysine 3-dioxygenase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    jumonji domain containing 7
    Names
    CG10133-PA
    JMJD7-PA
    NP_648651.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      13449187..13450283 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140394.2 → NP_648651.1  jumonji domain containing 7 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648651.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VU77
      Related
      FBpp0075567
      Conserved Domains (1) summary
      pfam13621
      Location:33 → 298
      Cupin_8; Cupin-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VU77 Q9VU77

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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