mip40 Myb-interacting protein 40 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: mip40provided by FlyBase
Official Full Name: Myb-interacting protein 40provided by FlyBase
Primary source: FLYBASE:FBgn0034430
Locus tag: Dmel_CG15119
See related: AllianceGenome:FB:FBgn0034430
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG15119; Dmel\CG15119; Mip40; p40
Summary: Involved in negative regulation of transcription by RNA polymerase II; oogenesis; and spermatogenesis. Part of DRM complex; Myb complex; and RNA polymerase II transcription regulator complex. Is active in nucleus. Is expressed in organism and testis. Orthologous to human LIN37 (lin-37 DREAM MuvB core complex component). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (19291105..19292196, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (15178610..15179701, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in eggshell chorion gene amplification	IC Inferred by Curator more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in oogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in spermatogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of DRM complex	IDA Inferred from Direct Assay more info	PubMed
part_of Myb complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Myb complex	IDA Inferred from Direct Assay more info	PubMed
part_of RNA polymerase II transcription regulator complex	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IDA Inferred from Direct Assay more info	PubMed
part_of transcription repressor complex	IEA Inferred from Electronic Annotation more info