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    Or10ad1c olfactory receptor family 10 subfamily AD member 1C [ Mus musculus (house mouse) ]

    Gene ID: 545140, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or10ad1cprovided by MGI
    Official Full Name
    olfactory receptor family 10 subfamily AD member 1Cprovided by MGI
    Primary source
    MGI:MGI:3030122
    See related
    Ensembl:ENSMUSG00000075427 AllianceGenome:MGI:3030122
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr288; MOR286-3P; GA_x5J8B7W76D0-7609197-7608973
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Expression
    Biased expression in cortex adult (RPKM 1.1), frontal lobe adult (RPKM 1.1) and 7 other tissues See more
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    Genomic context

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    See Or10ad1c in Genome Data Viewer
    Location:
    15 F1; 15 54.19 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (98083892..98093423, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (98186011..98195542, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_39652 Neighboring gene ankyrin repeat and SOCS box-containing 8 Neighboring gene STARR-seq mESC enhancer starr_39654 Neighboring gene STARR-positive B cell enhancer ABC_E5515 Neighboring gene coiled-coil domain containing 184 Neighboring gene predicted gene, 33909 Neighboring gene olfactory receptor family 10 subfamily AD member 1 Neighboring gene olfactory receptor family 10 subfamily AD member 1B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Contribution of individual olfactory receptors to odor-induced attractive or aversive behavior in mice. Horio N, et al. Nat Commun, 2019 Jan 14. PMID 30643144, Free PMC Article
    2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    olfactory receptor 288
    Names
    olfactory receptor MOR286-3P

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011733.2 → NP_001011733.2  olfactory receptor 288

      Status: VALIDATED

      Source sequence(s)
      AC105982, BG080619, C85333
      Consensus CDS
      CCDS49719.1
      UniProtKB/TrEMBL
      E9Q1P2, Q7TS14
      Related
      ENSMUSP00000132237.2, ENSMUST00000165379.8
      Conserved Domains (2) summary
      cd14964
      Location:67 → 89
      7tm_GPCRs; TM helix 2 [structural motif]
      cl28897
      Location:42 → 301
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      98083892..98093423 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017316704.3 → XP_017172193.2  olfactory receptor 288 isoform X1

      UniProtKB/TrEMBL
      E9Q1P2, Q7TS14
      Conserved Domains (2) summary
      cd14964
      Location:67 → 89
      7tm_GPCRs; TM helix 2 [structural motif]
      cl28897
      Location:42 → 301
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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