U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Or4a15 olfactory receptor family 4 subfamily A member 15 [ Mus musculus (house mouse) ]

    Gene ID: 258975, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Or4a15provided by MGI
    Official Full Name
    olfactory receptor family 4 subfamily A member 15provided by MGI
    Primary source
    MGI:MGI:3031068
    See related
    Ensembl:ENSMUSG00000075090 AllianceGenome:MGI:3031068
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MOR231-2; Olfr1234
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Or4a15 in Genome Data Viewer
    Location:
    2 E1; 2 50.03 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (89192827..89203990, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (89362483..89373646, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily C member 124 Neighboring gene olfactory receptor family 4 subfamily C member 125 Neighboring gene olfactory receptor 1235, pseudogene 1 Neighboring gene olfactory receptor GA_x5J8B7W62NC-653162-652995

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Sensitivity-dependent hierarchical receptor codes for odors. Hamana H, et al. Chem Senses, 2003 Feb. PMID 12588732
    2. Supersensitive detection and discrimination of enantiomers by dorsal olfactory receptors: evidence for hierarchical odour coding. Sato T, et al. Sci Rep, 2015 Sep 11. PMID 26361056, Free PMC Article
    3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    olfactory receptor 1234
    Names
    GA_x6K02T2Q125-50805620-50804676
    olfactory receptor MOR231-2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146973.2 → NP_667184.2  olfactory receptor 1234

      See identical proteins and their annotated locations for NP_667184.2

      Status: VALIDATED

      Source sequence(s)
      AL929555
      Consensus CDS
      CCDS16377.1
      UniProtKB/TrEMBL
      A2AVK5, Q8VGN1
      Related
      ENSMUSP00000097371.2, ENSMUST00000099783.2
      Conserved Domains (2) summary
      pfam00001
      Location:39 → 285
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:29 → 303
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      89192827..89203990 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017318612.1 → XP_017174101.1  olfactory receptor 1234 isoform X1

      UniProtKB/TrEMBL
      Q8VGN1
      Conserved Domains (1) summary
      cd15939
      Location:36 → 302
      7tmA_OR4A-like; olfactory receptor 4A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools