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    SMX2 mRNA splicing protein SMX2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850528, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SMX2
    Official Full Name
    mRNA splicing protein SMX2
    Primary source
    SGD:S000002965
    Locus tag
    YFL017W-A
    See related
    AllianceGenome:SGD:S000002965; FungiDB:YFL017W-A; VEuPathDB:YFL017W-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    SNP2; YFL018W-A
    Summary
    Predicted to contribute to RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of U2-type prespliceosome and spliceosomal snRNP complex. Orthologous to several human genes including SNRPG (small nuclear ribonucleoprotein polypeptide G). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SMX2 in Genome Data Viewer
    Location:
    chromosome: VI
    Exon count:
    1
    Sequence:
    Chromosome: VI; NC_001138.5 (103699..103932)

    Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene tRNA-Pro Neighboring gene dihydrolipoyl dehydrogenase Neighboring gene glucosamine 6-phosphate N-acetyltransferase Neighboring gene Mdj1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001138.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional characterization of nuclear localization signals in yeast Sm proteins. Bordonné R. Mol Cell Biol, 2000 Nov. PMID 11027265, Free PMC Article
    2. Stoichiometry of the Sm proteins in yeast spliceosomal snRNPs supports the heptamer ring model of the core domain. Walke S, et al. J Mol Biol, 2001 Apr 20. PMID 11302706
    3. Sm and Sm-like proteins belong to a large family: identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs. Séraphin B. EMBO J, 1995 May 1. PMID 7744014, Free PMC Article
    4. Interactions within the yeast Sm core complex: from proteins to amino acids. Camasses A, et al. Mol Cell Biol, 1998 Apr. PMID 9528767, Free PMC Article
    5. Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry. Neubauer G, et al. Proc Natl Acad Sci U S A, 1997 Jan 21. PMID 9012791, Free PMC Article

    See all (49) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    contributes_to RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spliceosomal snRNP assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of SMN-Sm protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U1 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U1 snRNP IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2-type prespliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2-type prespliceosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of U4 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U4/U6 x U5 tri-snRNP complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of U5 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U5 snRNP IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of spliceosomal tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    mRNA splicing protein SMX2
    NP_116636.1
    • Core Sm protein Sm G; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx3p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm G

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001138.5 Reference assembly

      Range
      103699..103932
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180864.1 → NP_116636.1  TPA: mRNA splicing protein SMX2 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_116636.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTL2, P40204
      UniProtKB/TrEMBL
      A7A221, B3LUJ1, C7GY92, G2WDC3, N1P6P9
      Conserved Domains (1) summary
      cd01719
      Location:3 → 75
      Sm_G; Sm protein G
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40204.1

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