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    CROT Carnitine O-octanoyltransferase [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43332, updated on 9-Dec-2024

    Summary

    Official Symbol
    CROTprovided by FlyBase
    Official Full Name
    Carnitine O-octanoyltransferaseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039543
    Locus tag
    Dmel_CG12428
    See related
    AllianceGenome:FB:FBgn0039543
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12428; CrOT; Dmel\CG12428
    Summary
    Predicted to enable carnitine O-octanoyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be active in peroxisome. Is expressed in adult head; embryonic hindgut; embryonic/larval oenocyte; and organism. Orthologous to human CROT (carnitine O-octanoyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See CROT in Genome Data Viewer
    Location:
    98B2-98B2; 3-94 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (27703379..27706751, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (23529101..23532473, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Accessory gland protein 98AB Neighboring gene HSPB1 associated protein 1 Neighboring gene ALG-2 interacting protein X Neighboring gene barentsz Neighboring gene uncharacterized protein Neighboring gene Ets at 98B

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables carnitine O-octanoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables carnitine O-octanoyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in peroxisome ISM
    Inferred from Sequence Model
    more info
    PubMed 
    located_in peroxisome ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    carnitine O-octanoyltransferase
    Names
    CG12428-PA
    CG12428-PB
    CG12428-PD
    CG12428-PE
    CG12428-PF
    CG12428-PG
    CROT-PA
    CROT-PB
    CROT-PD
    CROT-PE
    CROT-PF
    CROT-PG
    carnitine octanoyltransferase
    carnitine palmitoyltransferase
    NP_001334704.1
    NP_001334705.1
    NP_733230.1
    NP_733231.1
    NP_733232.1
    NP_733233.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      27703379..27706751 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170352.3NP_733231.1  carnitine O-octanoyltransferase, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733231.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VB02, Q9VB03
      Related
      FBpp0084605
      Conserved Domains (1) summary
      pfam00755
      Location:23605
      Carn_acyltransf; Choline/Carnitine o-acyltransferase
    2. NM_001347746.1NP_001334705.1  carnitine O-octanoyltransferase, isoform G [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VB02, Q9VB03
    3. NM_170351.2NP_733230.1  carnitine O-octanoyltransferase, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733230.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VB02, Q9VB03
      Related
      FBpp0084607
      Conserved Domains (1) summary
      pfam00755
      Location:23605
      Carn_acyltransf; Choline/Carnitine o-acyltransferase
    4. NM_001347745.1NP_001334704.1  carnitine O-octanoyltransferase, isoform F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VB02, Q9VB03
    5. NM_170353.3NP_733232.1  carnitine O-octanoyltransferase, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733232.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VB02, Q9VB03
      Related
      FBpp0084608
      Conserved Domains (1) summary
      pfam00755
      Location:23605
      Carn_acyltransf; Choline/Carnitine o-acyltransferase
    6. NM_170354.3NP_733233.1  carnitine O-octanoyltransferase, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733233.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VB02, Q9VB03
      Related
      FBpp0084609
      Conserved Domains (1) summary
      pfam00755
      Location:23605
      Carn_acyltransf; Choline/Carnitine o-acyltransferase