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    CG5098 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37063, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5098provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034300
    Locus tag
    Dmel_CG5098
    See related
    AllianceGenome:FB:FBgn0034300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5098
    Summary
    Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in embryonic brain and organism. Human ortholog(s) of this gene implicated in Smith-Magenis syndrome. Orthologous to several human genes including TCF20 (transcription factor 20). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5098 in Genome Data Viewer
    Location:
    55B4-55B5; 2-84 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18094940..18101031)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13982445..13988536)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45022 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila Trf4-1 involves in mRNA and primary miRNA transcription. Liu Y, et al. Biochem Biophys Res Commun, 2019 Apr 16. PMID 30837153
    2. Drosophila MCRS2 associates with RNA polymerase II complexes to regulate transcription. Andersen DS, et al. Mol Cell Biol, 2010 Oct. PMID 20679484, Free PMC Article
    3. The nonspecific lethal complex is a transcriptional regulator in Drosophila. Raja SJ, et al. Mol Cell, 2010 Jun 25. PMID 20620954
    4. Seizure control through genetic and pharmacological manipulation of Pumilio in Drosophila: a key component of neuronal homeostasis. Lin WH, et al. Dis Model Mech, 2017 Feb 1. PMID 28067623, Free PMC Article
    5. A genome-wide resource for the analysis of protein localisation in Drosophila. Sarov M, et al. Elife, 2016 Feb 20. PMID 26896675, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5098-PA
    CG5098-PB
    CG5098-PC
    CG5098-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      18094940..18101031
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137447.4 → NP_611291.1  uncharacterized protein Dmel_CG5098, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611291.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8DYH9, Q6AWG9
      Related
      FBpp0085911
      Conserved Domains (1) summary
      cl22851
      Location:982 → 1198
      PHD_SF; PHD finger superfamily

    2. NM_001103893.2 → NP_001097363.1  uncharacterized protein Dmel_CG5098, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097363.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6AWG9
      Conserved Domains (1) summary
      cl22851
      Location:1072 → 1288
      PHD_SF; PHD finger superfamily

    3. NM_001274137.1 → NP_001261066.1  uncharacterized protein Dmel_CG5098, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261066.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KFU8
      Conserved Domains (1) summary
      cl22851
      Location:1068 → 1284
      PHD_SF; PHD finger superfamily

    4. NM_001316427.1 → NP_001303356.1  uncharacterized protein Dmel_CG5098, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A126GUN5
      Conserved Domains (1) summary
      cl22851
      Location:1068 → 1284
      PHD_SF; PHD finger superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KFU8 A0A0B4KFU8
    A0A126GUN5 A0A126GUN5
    Q6AWG9.1 Q6AWG9

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