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    CG4615 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31656, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4615provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029935
    Locus tag
    Dmel_CG4615
    See related
    AllianceGenome:FB:FBgn0029935
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4615
    Summary
    Predicted to enable pore-forming activity. Predicted to be located in membrane. Is expressed in organism. Orthologous to human MMD (monocyte to macrophage differentiation associated) and MMD2 (monocyte to macrophage differentiation associated 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4615 in Genome Data Viewer
    Location:
    6F5-6F5; 1-19 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (7098578..7102300, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (6992611..6996333, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Sex lethal Neighboring gene mir-4956 stem loop Neighboring gene long non-coding RNA:CR46494 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene frizzled 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A link between impaired purine nucleotide synthesis and apoptosis in Drosophila melanogaster. Holland C, et al. Genetics, 2011 Jun. PMID 21441212, Free PMC Article
    2. A cis-regulatory-directed pipeline for the identification of genes involved in cardiac development and disease. Nim HT, et al. Genome Biol, 2021 Dec 15. PMID 34906219, Free PMC Article
    3. The evolution of constitutively active humoral immune defenses in Drosophila populations under high parasite pressure. Zhou SO, et al. PLoS Pathog, 2024 Jan. PMID 38206983, Free PMC Article
    4. Identification of Drosophila gene products required for phagocytosis of Candida albicans. Stroschein-Stevenson SL, et al. PLoS Biol, 2006 Jan. PMID 16336044, Free PMC Article
    5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables pore-forming activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4615-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      7098578..7102300 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132154.3 → NP_572382.1  uncharacterized protein Dmel_CG4615 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572382.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W3S5
      Related
      FBpp0070979
      Conserved Domains (1) summary
      TIGR01065
      Location:85 → 304
      hlyIII; channel protein, hemolysin III family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W3S5 Q9W3S5

    Gene LinkOut

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