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    betaTub60D beta-Tubulin at 60D [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37888, updated on 27-Dec-2024

    Summary

    Official Symbol
    betaTub60Dprovided by FlyBase
    Official Full Name
    beta-Tubulin at 60Dprovided by FlyBase
    Primary source
    FLYBASE:FBgn0288686
    Locus tag
    Dmel_CG3401
    See related
    AllianceGenome:FB:FBgn0288686
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    143391_i_at; 3t; B3t; BETA 60D; beta-tub; beta-Tub60D; beta-Tub6D; beta3; beta3 TU; beta3-Tub; beta3-tubulin; beta3t; beta3tub; beta3Tub; beta3TUB; beta3Tub60D; beta60C; betaTub; betaTub3; betaTub60C; betatub60D; betatubulin; beta[[3]] tubulin; beta[[3]]-Tub; beta[[3]]-tubulin; CG3401; D.m.BETA-60D; Dmbeta3; Dmel\CG3401; DTB3; p50; p50/tubulin; p53; p53/tubulin; Pin; T; Tac; Tub; Tub2E; Tub60D; tubulin
    Summary
    A structural constituent of cytoskeleton. Involved in axon guidance; larval behavior; and response to light stimulus. Located in microtubule. Is expressed in several structures, including gonad; imaginal disc; muscle cell; muscle system; and scolopidial dendritic cap cell. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See betaTub60D in Genome Data Viewer
    Location:
    60C6-60C6; 2-106 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24305881..24313099)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20193404..20200622)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene nervy Neighboring gene mir-4985 stem loop Neighboring gene Fatty acid transport protein 3 Neighboring gene long non-coding RNA:CR44810 Neighboring gene slow border cells

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in larval behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in microtubule-based process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to light stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in microtubule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    beta-Tubulin at 60D
    Names
    60C beta tubulin
    B3-tubulin
    CG3401-PA
    CG3401-PB
    Pin
    b-3 tubulin
    b3 tubulin
    beta 3 tubulin
    beta tubulin
    beta-3 tubulin
    beta-3-tubulin
    beta-3tubulin
    beta-Tubulin
    beta-Tubulin at 60A
    beta-tubulin 60D
    beta-tubulin at 60D
    beta-tubulin60D
    beta3 tubulin
    beta3-tubulin
    beta3tubulin
    betaTub60D-PA
    betaTub60D-PB
    betatubulin
    tack
    tubulin
    tubulin b-3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24305881..24313099
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079118.3NP_523842.2  beta-Tubulin at 60D, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523842.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P08841, Q6I8M0, Q6I8M1, Q9W184
      UniProtKB/TrEMBL
      E0R982
      Related
      FBpp0072177
      Conserved Domains (2) summary
      PLN00220
      Location:1450
      PLN00220; tubulin beta chain; Provisional
      cd02187
      Location:2432
      beta_tubulin; The beta-tubulin family
    2. NM_001299906.1NP_001286835.1  beta-Tubulin at 60D, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286835.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LGH1, E0R982
      Conserved Domains (2) summary
      PLN00220
      Location:1449
      PLN00220; tubulin beta chain; Provisional
      cd02187
      Location:2431
      beta_tubulin; The beta-tubulin family