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    RpL27A Ribosomal protein L27A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33654, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RpL27Aprovided by FlyBase
    Official Full Name
    Ribosomal protein L27Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0285948
    Locus tag
    Dmel_CG15442
    See related
    AllianceGenome:FB:FBgn0285948
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Posey257; CG15442; Dmel\CG15442; l(2)24EFh; l(2)24Fb; l(2)SH0840; l(2)SH2 0840; L15; M; M(2)24F; M(2)24F-1; M(2)z; M(2)Z; M(2L)z; Mz; M[[z]]; Rp L27A; rpL27a; RpL27a; RpL27a2; RpL27Aa; RpL27Ab
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytosolic ribosome. Is expressed in adult head; adult heart; and organism. Used to study intrinsic cardiomyopathy. Orthologous to human RPL27A (ribosomal protein L27a). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See RpL27A in Genome Data Viewer
    Location:
    24F3-24F3; 2-12 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4457186..4458364, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4457186..4458364, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene tRNA Selenocysteine associated protein Neighboring gene NADH dehydrogenase (ubiquinone) B8 subunit Neighboring gene GS1-like Neighboring gene ncRNA Neighboring gene mitochondrial ribosomal protein L27 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Protocol for assessing translation in living Drosophila imaginal discs by O-propargyl-puromycin incorporation. Kiparaki M, et al. STAR Protoc, 2023 Dec 15. PMID 37862174, Free PMC Article
    2. The Drosophila melanogaster homolog of ribosomal protein L27a. Garwood J, et al. Biochem Biophys Res Commun, 1994 Jan 28. PMID 8297386
    3. Identification of a cDNA clone encoding DIP1-binding protein in Drosophila melanogaster. De Felice B, et al. Mol Biol Rep, 2004 Sep. PMID 15560371
    4. Localization of minutes to specific polytene chromosome bands by means of overlapping duplications. Broderick DJ, et al. Genetics, 1982 Sep. PMID 7129093, Free PMC Article
    5. Properties and evolutionary potential of newly induced tandem duplications in Drosophila melanogaster. Roberts PA, et al. Genetics, 1982 Sep. PMID 6813191, Free PMC Article

    See all (88) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. L27a protein, via interaction with DIP1, could be involved in protein synthesis as well as in cell cycle regulation
      Title: Identification of a cDNA clone encoding DIP1-binding protein in Drosophila melanogaster.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome HDA PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytosolic ribosome HDA PubMed 
    located_in cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal protein L27A
    Names
    CG15442-PA
    CG15442-PC
    CG15442-PD
    RpL27A-PA
    RpL27A-PC
    RpL27A-PD
    lethal (2) SH0840
    minute
    minute (2) 24F
    ribosomal protein L27a

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4457186..4458364 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001201760.2 → NP_001188689.2  ribosomal protein L27A, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188689.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P41092, Q94530, Q9VR02
      UniProtKB/TrEMBL
      M9MRC9
      Conserved Domains (1) summary
      PTZ00160
      Location:7 → 149
      PTZ00160; 60S ribosomal protein L27a; Provisional

    2. NM_001298672.1 → NP_001285601.1  ribosomal protein L27A, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285601.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P41092, Q94530, Q9VR02
      UniProtKB/TrEMBL
      M9MRC9
      Conserved Domains (1) summary
      PTZ00160
      Location:7 → 149
      PTZ00160; 60S ribosomal protein L27a; Provisional

    3. NM_057615.6 → NP_476963.1  ribosomal protein L27A, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476963.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P41092, Q94530, Q9VR02
      UniProtKB/TrEMBL
      M9MRC9
      Related
      FBpp0077142
      Conserved Domains (1) summary
      PTZ00160
      Location:7 → 149
      PTZ00160; 60S ribosomal protein L27a; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9MRC9 M9MRC9
    P41092.2 P41092

    Gene LinkOut

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