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    CG14401 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35358, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14401provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032900
    Locus tag
    Dmel_CG14401
    See related
    AllianceGenome:FB:FBgn0032900
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14401
    Summary
    Predicted to be involved in regulation of cholinergic synaptic transmission and sleep. Predicted to be active in plasma membrane. Is expressed in adult heart. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14401 in Genome Data Viewer
    Location:
    38F3-38F3; 2-54 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20869854..20871565)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20869854..20871565)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44981 Neighboring gene uncharacterized protein Neighboring gene skywalker Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family. Tanaka K, et al. Mol Biol Evol, 2015 Jul. PMID 25743545, Free PMC Article
    2. The Ly6 neurotoxin-like molecule target of wit regulates spontaneous neurotransmitter release at the developing neuromuscular junction in Drosophila. Kim NC, et al. Dev Neurobiol, 2012 Dec. PMID 22467519
    3. Crooked, coiled and crimpled are three Ly6-like proteins required for proper localization of septate junction components. Nilton A, et al. Development, 2010 Jul. PMID 20570942, Free PMC Article
    4. boudin is required for septate junction organisation in Drosophila and codes for a diffusible protein of the Ly6 superfamily. Hijazi A, et al. Development, 2009 Jul. PMID 19502482
    5. Adaptation to Chronic Nutritional Stress Leads to Reduced Dependence on Microbiota in Drosophila melanogaster. Erkosar B, et al. mBio, 2017 Oct 24. PMID 29066546, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in positive regulation of voltage-gated potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of synaptic transmission, cholinergic IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sleep IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14401-PA
    CG14401-PB
    CG14401-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      20869854..20871565
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136228.3 → NP_610072.2  uncharacterized protein Dmel_CG14401, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610072.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      D5A7S1, Q9VIH8
      Related
      FBpp0080959

    2. NM_001259186.2 → NP_001246115.1  uncharacterized protein Dmel_CG14401, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246115.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NDC5

    3. NM_001273718.1 → NP_001260647.1  uncharacterized protein Dmel_CG14401, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260647.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D5A7S1, M9PGD2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9NDC5 M9NDC5
    M9PGD2 M9PGD2
    Q9VIH8 Q9VIH8

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