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    CG8312 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41163, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8312provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037720
    Locus tag
    Dmel_CG8312
    See related
    AllianceGenome:FB:FBgn0037720
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8312
    Summary
    Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Is expressed in several structures, including antennal anlage; central brain anlage; dorsal ectoderm; epithelium; and head epidermis primordium. Orthologous to several human genes including FAM43B (family with sequence similarity 43 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8312 in Genome Data Viewer
    Location:
    85D27-85E1; 3-49 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9591309..9625073)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5417031..5450795)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene P58IPK Neighboring gene bocksbeutel Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic basis of offspring number-body weight tradeoff in Drosophila melanogaster. Akhund-Zade J, et al. G3 (Bethesda), 2021 Jul 14. PMID 33871609, Free PMC Article
    2. Unique and shared functions of nuclear lamina LEM domain proteins in Drosophila. Barton LJ, et al. Genetics, 2014 Jun. PMID 24700158, Free PMC Article
    3. m(6)A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination. Haussmann IU, et al. Nature, 2016 Dec 8. PMID 27919081
    4. Target genes of Dpp/BMP signaling pathway revealed by transcriptome profiling in the early D.melanogaster embryo. Dominguez C, et al. Gene, 2016 Oct 10. PMID 27397649
    5. GWAS for Lifespan and Decline in Climbing Ability in Flies upon Dietary Restriction Reveal decima as a Mediator of Insulin-like Peptide Production. Wilson KA, et al. Curr Biol, 2020 Jul 20. PMID 32502405, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8312-PA
    CG8312-PB
    CG8312-PC
    CG8312-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      9591309..9625073
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141661.2 → NP_649918.1  uncharacterized protein Dmel_CG8312, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649918.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VHA6
      Related
      FBpp0081553
      Conserved Domains (1) summary
      pfam14719
      Location:263 → 442
      PID_2; Phosphotyrosine interaction domain (PTB/PID)

    2. NM_001275498.1 → NP_001262427.1  uncharacterized protein Dmel_CG8312, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262427.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGM0
      Conserved Domains (1) summary
      pfam14719
      Location:263 → 441
      PID_2; Phosphotyrosine interaction domain (PTB/PID)

    3. NM_001275499.1 → NP_001262428.1  uncharacterized protein Dmel_CG8312, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262428.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGM0
      Conserved Domains (1) summary
      pfam14719
      Location:263 → 441
      PID_2; Phosphotyrosine interaction domain (PTB/PID)

    4. NM_176438.2 → NP_788615.1  uncharacterized protein Dmel_CG8312, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788615.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86BA6
      Related
      FBpp0081554
      Conserved Domains (1) summary
      cl17171
      Location:1 → 23
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KGM0 A0A0B4KGM0
    Q86BA6 Q86BA6
    Q8MRF2 Q8MRF2
    Q9VHA6 Q9VHA6

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