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    CG5335 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37140, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5335provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034365
    Locus tag
    Dmel_CG5335
    See related
    AllianceGenome:FB:FBgn0034365
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5335
    Summary
    Predicted to enable carbohydrate binding activity and galactoside binding activity. Is expressed in adult head. Orthologous to human LGALS8 (galectin 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5335 in Genome Data Viewer
    Location:
    55E2-55E2; 2-86 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18621541..18622986)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14509046..14510491)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Autophagy-related 7 Neighboring gene Secretory 6 Neighboring gene Cystathionine gamma-lyase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila. Juhász G, et al. Genes Dev, 2007 Dec 1. PMID 18056421, Free PMC Article
    2. Galectinomics: finding themes in complexity. Cooper DN. Biochim Biophys Acta, 2002 Sep 19. PMID 12223271
    3. Galectins induced from hemocytes bridge phosphatidylserine and N-glycosylated Drpr/CED-1 receptor during dendrite pruning. Sung HH, et al. Nat Commun, 2024 Aug 27. PMID 39191750, Free PMC Article
    4. 2'3'-cGAMP triggers a STING- and NF-κB-dependent broad antiviral response in Drosophila. Cai H, et al. Sci Signal, 2020 Dec 1. PMID 33262294
    5. Genetic and Genomic Response to Selection for Food Consumption in Drosophila melanogaster. Garlapow ME, et al. Behav Genet, 2017 Mar. PMID 27704301, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosylation-dependent protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in synapse pruning IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5335-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      18621541..18622986
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137505.4 → NP_611349.2  uncharacterized protein Dmel_CG5335 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611349.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBB1, Q95SA3
      Related
      FBpp0085887
      Conserved Domains (2) summary
      cd00070
      Location:172 → 297
      GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...
      pfam00337
      Location:5 → 140
      Gal-bind_lectin; Galactoside-binding lectin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZBB1 A1ZBB1
    Q95SA3 Q95SA3

    Gene LinkOut

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