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    TCD1 tRNA threonylcarbamoyladenosine dehydratase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856392, updated on 14-Nov-2024

    Summary

    Official Symbol
    TCD1
    Official Full Name
    tRNA threonylcarbamoyladenosine dehydratase
    Primary source
    SGD:S000001045
    Locus tag
    YHR003C
    See related
    AllianceGenome:SGD:S000001045; FungiDB:YHR003C; VEuPathDB:YHR003C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables tRNA threonylcarbamoyladenosine dehydratase. Involved in cyclic threonylcarbamoyladenosine biosynthetic process. Located in mitochondrial outer membrane. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See TCD1 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (110028..111317, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene ubiquinol--cytochrome-c reductase subunit 10 Neighboring gene coenzyme A transporter Neighboring gene Nem1-Spo7 phosphatase catalytic subunit NEM1 Neighboring gene guanine nucleotide-binding protein subunit alpha

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    tRNA threonylcarbamoyladenosine dehydratase
    NP_011866.1
    • tRNA threonylcarbamoyladenosine dehydratase; required for the ct6A tRNA base modification, where an adenosine at position 37 is modified to form a cyclized active ester with an oxazolone ring; localized to the mitochondrial outer membrane; TCD1 has a paralog, TCD2, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      110028..111317 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179133.1NP_011866.1  TPA: tRNA threonylcarbamoyladenosine dehydratase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011866.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKU6, P38756
      UniProtKB/TrEMBL
      A6ZSQ5, B3LSC1, C8ZA69, G2WF69
      Conserved Domains (1) summary
      COG1179
      Location:50309
      TcdA; tRNA A37 threonylcarbamoyladenosine dehydratase [Translation, ribosomal structure and biogenesis]