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    PPP4R2r Protein phosphatase 4 regulatory subunit 2-related protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31979, updated on 9-Dec-2024

    Summary

    Official Symbol
    PPP4R2rprovided by FlyBase
    Official Full Name
    Protein phosphatase 4 regulatory subunit 2-related proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030208
    Locus tag
    Dmel_CG2890
    See related
    AllianceGenome:FB:FBgn0030208
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD29930; CG2890; Dmel\CG2890; PP4R; PP4r2; PP4R2; PP4R2r; Ppp4R2; PPP4R2; R2
    Summary
    Predicted to enable protein phosphatase regulator activity. Involved in mitotic cell cycle; negative regulation of peptidoglycan recognition protein signaling pathway; and negative regulation of smoothened signaling pathway. Located in chromosome, centromeric region. Part of protein phosphatase 4 complex. Orthologous to human PPP4R2 (protein phosphatase 4 regulatory subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See PPP4R2r in Genome Data Viewer
    Location:
    9D1-9D2; 1-32 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10478838..10481943)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10372871..10375976)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene no circadian temperature entrainment Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene sprint Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein phosphatase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein phosphatase regulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromosome, centromeric region IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of protein phosphatase 4 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of protein phosphatase 4 complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of protein phosphatase 4 complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein phosphatase 4 regulatory subunit 2-related protein
    Names
    CG2890-PA
    CG2890-PB
    CG2890-PC
    CG2890-PD
    PP4 regulatory subunit
    PPP4R2r-PA
    PPP4R2r-PB
    PPP4R2r-PC
    PPP4R2r-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      10478838..10481943
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272481.2NP_001259410.1  protein phosphatase 4 regulatory subunit 2-related protein, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259410.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PGT6
      Conserved Domains (1) summary
      pfam09184
      Location:1205
      PPP4R2; PPP4R2
    2. NM_167232.2NP_727427.1  protein phosphatase 4 regulatory subunit 2-related protein, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727427.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q960Z5, Q9NFT0, Q9W2U4
      Related
      FBpp0071386
      Conserved Domains (1) summary
      pfam09184
      Location:10292
      PPP4R2; PPP4R2
    3. NM_206677.2NP_996400.1  protein phosphatase 4 regulatory subunit 2-related protein, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996400.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q960Z5, Q9NFT0, Q9W2U4
      Conserved Domains (1) summary
      pfam09184
      Location:10292
      PPP4R2; PPP4R2
    4. NM_080344.3NP_525083.2  protein phosphatase 4 regulatory subunit 2-related protein, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_525083.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q960Z5, Q9NFT0, Q9W2U4
      Related
      FBpp0071387
      Conserved Domains (1) summary
      pfam09184
      Location:10292
      PPP4R2; PPP4R2