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    Cdk12 Cyclin-dependent kinase 12 [ Anopheles gambiae (African malaria mosquito) ]

    Gene ID: 1278447, updated on 3-Dec-2024

    Summary

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    Gene symbol
    Cdk12
    Gene description
    Cyclin-dependent kinase 12
    See related
    VectorBase:AGAMI1_003914
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Anopheles gambiae
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
    Also known as
    AGAP004780
    Orthologs
    fruit fly all
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    Genomic context

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    See Cdk12 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_12 current idAnoGambNW_F1_1 (GCF_943734735.2) 2 NC_064601.1 (67092336..67101098, complement)

    Chromosome 2 - NC_064601.1Genomic Context describing neighboring genes Neighboring gene xaa-Pro dipeptidase Neighboring gene zinc finger BED domain-containing protein 4-like Neighboring gene bolA-like protein 3 Neighboring gene beta-1,4-N-acetylgalactosaminyltransferase bre-4 Neighboring gene tubulin folding cofactor D

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_064601.1 Chromosome 2 Reference idAnoGambNW_F1_1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II CTD heptapeptide repeat kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cyclin/CDK positive transcription elongation factor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclin-dependent kinase 12
    Names
    AGAP004780-PA
    cyclin-dependent kinase 12/13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_943734735.2-RS_2023_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference idAnoGambNW_F1_1 Primary Assembly

    Genomic

    1. NC_064601.1 Reference idAnoGambNW_F1_1 Primary Assembly

      Range
      67092336..67101098 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_061642933.1 → XP_061498917.1  cyclin-dependent kinase 12 isoform X4

      UniProtKB/TrEMBL
      A0A1S4GM55

    2. XM_061642932.1 → XP_061498916.1  cyclin-dependent kinase 12 isoform X3

      UniProtKB/TrEMBL
      A0A1S4GM55

    3. XM_061642930.1 → XP_061498914.1  cyclin-dependent kinase 12 isoform X1

      UniProtKB/TrEMBL
      A0A1S4GM55

    4. XM_061642929.1 → XP_061498913.1  cyclin-dependent kinase 12 isoform X1

      UniProtKB/TrEMBL
      A0A1S4GM55

    5. XM_061642931.1 → XP_061498915.1  cyclin-dependent kinase 12 isoform X2

      UniProtKB/TrEMBL
      A0A1S4GM55

    6. XM_061642928.1 → XP_061498912.1  cyclin-dependent kinase 12 isoform X1

      UniProtKB/TrEMBL
      A0A1S4GM55

    7. XM_061642934.1 → XP_061498918.1  cyclin-dependent kinase 12 isoform X4

      UniProtKB/TrEMBL
      A0A1S4GM55
    Nucleotide Protein Strain
    Heading Accession and Version

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