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    polo Serine/threonine-protein kinase polo [ Anopheles gambiae (African malaria mosquito) ]

    Gene ID: 1274084, updated on 22-Jun-2024

    Summary

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    Gene symbol
    polo
    Gene description
    Serine/threonine-protein kinase polo
    See related
    VectorBase:AGAMI1_011846
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Anopheles gambiae
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
    Also known as
    AGAP004239
    Orthologs
    fruit fly all
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    Genomic context

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    See polo in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_12 current idAnoGambNW_F1_1 (GCF_943734735.2) 2 NC_064601.1 (51559681..51563542)

    Chromosome 2 - NC_064601.1Genomic Context describing neighboring genes Neighboring gene restin homolog Neighboring gene chaperonin containing TCP1 subunit 1 Neighboring gene cyclin-C Neighboring gene GPALPP motifs-containing protein 1 Neighboring gene phosphatidate cytidylyltransferase, mitochondrial

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_064601.1 Chromosome 2 Reference idAnoGambNW_F1_1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pilot Anopheles gambiae full-length cDNA study: sequencing and initial characterization of 35,575 clones. Gomez SM, et al. Genome Biol, 2005. PMID 15833126, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase polo
    Names
    AGAP004239-PA
    polo-like kinase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_943734735.2-RS_2023_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference idAnoGambNW_F1_1 Primary Assembly

    Genomic

    1. NC_064601.1 Reference idAnoGambNW_F1_1 Primary Assembly

      Range
      51559681..51563542
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_313155.6 → XP_313155.3  serine/threonine-protein kinase polo

      See identical proteins and their annotated locations for XP_313155.3

      UniProtKB/TrEMBL
      Q7PQP3
      Conserved Domains (3) summary
      cd13117
      Location:490 → 570
      POLO_box_2; Second polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
      cd13118
      Location:388 → 475
      POLO_box_1; First polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
      cd14099
      Location:25 → 279
      STKc_PLK; Catalytic domain of the Serine/Threonine Kinases, Polo-like kinases
    Nucleotide Protein Strain
    Heading Accession and Version

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    Research Materials