U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PF3D7_1417800 DNA replication licensing factor MCM2 [ Plasmodium falciparum 3D7 ]

    Gene ID: 811758, updated on 12-Sep-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    PF3D7_1417800
    Gene description
    DNA replication licensing factor MCM2
    Locus tag
    PF3D7_1417800
    See related
    PlasmoDB:PF3D7_1417800; VEuPathDB:PF3D7_1417800
    Gene type
    protein coding
    RNA name
    DNA replication licensing factor MCM2
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PF3D7_1417800 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    2
    Sequence:
    Chromosome: 14; NC_037283.1 (753389..756440)

    Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene conserved protein, unknown function Neighboring gene ATP synthase-associated protein, putative Neighboring gene ubiquitin fusion degradation protein 1, putative

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037283.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Pre-replication complex organization in the atypical DNA replication cycle of Plasmodium falciparum: characterization of the mini-chromosome maintenance (MCM) complex formation. Patterson S, et al. Mol Biochem Parasitol, 2006 Jan. PMID 16257456
    2. A mutagenesis screen for essential plastid biogenesis genes in human malaria parasites. Tang Y, et al. PLoS Biol, 2019 Feb. PMID 30726238, Free PMC Article
    3. Functional Characterization of the m(6)A-Dependent Translational Modulator PfYTH.2 in the Human Malaria Parasite. Sinha A, et al. mBio, 2021 Apr 27. PMID 33906926, Free PMC Article
    4. Identification of Plasmodium falciparum nuclear proteins by mass spectrometry and proposed protein annotation. Briquet S, et al. PLoS One, 2018. PMID 30379851, Free PMC Article
    5. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Oehring SC, et al. Genome Biol, 2012 Nov 26. PMID 23181666, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables RNA binding HDA PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within plastid organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    DNA replication licensing factor MCM2
    XP_001348350.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037283.1 Reference assembly

      Range
      753389..756440
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001348314.1 → XP_001348350.1  DNA replication licensing factor MCM2 [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001348350.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024V145, A0A024WFV8, A0A024X0B4, A0A0L1I9Y6, A0A0L7M8N7, Q8ILR7, W4IAP8, W4IWT2, W7F7Z5, W7JGY1, W7JZ79
      Conserved Domains (2) summary
      smart00350
      Location:306 → 845
      MCM; minichromosome maintenance proteins
      pfam14551
      Location:217 → 292
      MCM_N; MCM N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.