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    PF3D7_1438500 cleavage and polyadenylation specificity factor subunit 3, putative [ Plasmodium falciparum 3D7 ]

    Gene ID: 811946, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1438500
    Gene description
    cleavage and polyadenylation specificity factor subunit 3, putative
    Locus tag
    PF3D7_1438500
    See related
    PlasmoDB:PF3D7_1438500; VEuPathDB:PF3D7_1438500
    Gene type
    protein coding
    RNA name
    cleavage and polyadenylation specificity factor subunit 3, putative
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1438500 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    1
    Sequence:
    Chromosome: 14; NC_037283.1 (1557527..1560157, complement)

    Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene tRNA-Met Neighboring gene metacaspase-2 Neighboring gene conserved protein, unknown function Neighboring gene DNA primase small subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037283.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue. Sonoiki E, et al. Nat Commun, 2017 Mar 6. PMID 28262680, Free PMC Article
    2. Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis. Palencia A, et al. EMBO Mol Med, 2017 Mar. PMID 28148555, Free PMC Article
    3. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Oehring SC, et al. Genome Biol, 2012 Nov 26. PMID 23181666, Free PMC Article
    4. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Process Evidence Code Pubs
    acts_upstream_of_or_within response to xenobiotic stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mRNA cleavage and polyadenylation specificity factor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cleavage and polyadenylation specificity factor subunit 3, putative

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037283.1 Reference assembly

      Range
      1557527..1560157 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001348502.1 → XP_001348538.1  cleavage and polyadenylation specificity factor subunit 3, putative [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001348538.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024VKU0, A0A024WHH2, A0A024WZL9, A0A0L1IFG8, A0A0L7K5H2, Q8IL83, W4IVL6, W7F4Q3, W7FAL5, W7JM26, W7JQN4
      Conserved Domains (2) summary
      smart01098
      Location:594 → 803
      CPSF73-100_C; This is the C-terminal conserved region of the pre-mRNA 3'-end-processing of the polyadenylation factor CPSF-73/CPSF-100 proteins
      COG1236
      Location:9 → 501
      YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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