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    VMA5 H(+)-transporting V1 sector ATPase subunit C [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853782, updated on 9-Dec-2024

    Summary

    Official Symbol
    VMA5
    Official Full Name
    H(+)-transporting V1 sector ATPase subunit C
    Primary source
    SGD:S000001563
    Locus tag
    YKL080W
    See related
    AllianceGenome:SGD:S000001563; FungiDB:YKL080W; VEuPathDB:YKL080W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    CSL5; VAT3
    Summary
    Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in vacuolar acidification. Located in fungal-type vacuole membrane. Orthologous to human ATP6V1C1 (ATPase H+ transporting V1 subunit C1) and ATP6V1C2 (ATPase H+ transporting V1 subunit C2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See VMA5 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (285030..286208)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene ribosome biosynthesis protein RRP14 Neighboring gene translation elongation factor EF1B gamma Neighboring gene ncRNA Neighboring gene Smy1p Neighboring gene RNA helicase

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    H(+)-transporting V1 sector ATPase subunit C
    NP_012843.1
    • Subunit C of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane; the V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase) has eight subunits

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      285030..286208
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179646.1NP_012843.1  TPA: H(+)-transporting V1 sector ATPase subunit C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012843.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXK7, P31412
      UniProtKB/TrEMBL
      A6ZZN6, B3LR11, B5VM76, C7GVM8, C8ZC93, G2WHV2, N1P072
      Conserved Domains (2) summary
      COG5127
      Location:6392
      COG5127; Vacuolar H+-ATPase V1 sector, subunit C [Energy production and conversion]
      cd14785
      Location:6686
      V-ATPase_C; 3-helical coiled coil [structural motif]