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    TEF4 translation elongation factor EF1B gamma [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853781, updated on 3-Nov-2024

    Summary

    Official Symbol
    TEF4
    Official Full Name
    translation elongation factor EF1B gamma
    Primary source
    SGD:S000001564
    Locus tag
    YKL081W
    See related
    AllianceGenome:SGD:S000001564; FungiDB:YKL081W; VEuPathDB:YKL081W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    EFC1
    Summary
    Enables guanyl-nucleotide exchange factor activity. Involved in translational elongation. Located in cytoplasmic stress granule. Orthologous to human EEF1G (eukaryotic translation elongation factor 1 gamma). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See TEF4 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    2
    Sequence:
    Chromosome: XI; NC_001143.9 (282891..284455)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Hot13p Neighboring gene ribosome biosynthesis protein RRP14 Neighboring gene ncRNA Neighboring gene H(+)-transporting V1 sector ATPase subunit C Neighboring gene Smy1p

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables translation elongation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables translation elongation factor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in translational elongation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in translational elongation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in translational elongation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic stress granule HDA PubMed 
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in ribosome TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    translation elongation factor EF1B gamma
    NP_012842.1
    • Gamma subunit of translational elongation factor eEF1B; stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing eEF1A (Tef1p/Tef2p) from the ribosomal complex

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      282891..284455
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179647.1NP_012842.1  TPA: translation elongation factor EF1B gamma [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012842.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXK6, P36008
      UniProtKB/TrEMBL
      B3LR10, C8ZC92, N1P2A1
      Conserved Domains (3) summary
      cd03181
      Location:89211
      GST_C_EF1Bgamma_like; Glutathione S-transferase C-terminal-like, alpha helical domain of the Gamma subunit of Elongation Factor 1B and similar proteins
      cd03044
      Location:472
      GST_N_EF1Bgamma; GST_N family, Gamma subunit of Elongation Factor 1B (EFB1gamma) subfamily; EF1Bgamma is part of the eukaryotic translation elongation factor-1 (EF1) complex which plays a central role in the elongation cycle during protein biosynthesis. EF1 consists of ...
      pfam00647
      Location:253356
      EF1G; Elongation factor 1 gamma, conserved domain