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    GBF3 G-box binding factor 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819235, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GBF3
    Official Full Name
    G-box binding factor 3
    Primary source
    TAIR:AT2G46270
    Locus tag
    AT2G46270
    See related
    Araport:AT2G46270
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    BZIP TRANSCRIPTION FACTOR; G-box binding factor 3; T3F17.8
    Summary
    encodes a bZIP G-box binding protein whose expression is induced by ABA. It has been shown to bind to Adh that contains the G-box and is induced by cold and water deprivation. GBF3 has been shown to be expressed mostly in the root and dark-grown leaves. GBF3 can act as homodimers and as heterodimers with GFB1, GBF2 and GBF4. In addition, GBF3###Os DNA binding activity is enhanced by GIP1, GPRI1 and GPRI2.
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    Genomic context

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    See GBF3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (19000180..19003403)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene BTB/POZ/Kelch-associated protein Neighboring gene TGF-beta receptor interacting protein 1 Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GBF3 transcription factor imparts drought tolerance in Arabidopsis thaliana. Ramegowda V, et al. Sci Rep, 2017 Aug 22. PMID 28831141, Free PMC Article
    2. Transcription factor veracity: is GBF3 responsible for ABA-regulated expression of Arabidopsis Adh? Lu G, et al. Plant Cell, 1996 May. PMID 8672884, Free PMC Article
    3. Heterodimerization between light-regulated and ubiquitously expressed Arabidopsis GBF bZIP proteins. Schindler U, et al. EMBO J, 1992 Apr. PMID 1373374, Free PMC Article
    4. Isolation and characterization of a fourth Arabidopsis thaliana G-box-binding factor, which has similarities to Fos oncoprotein. Menkens AE, et al. Proc Natl Acad Sci U S A, 1994 Mar 29. PMID 8146148, Free PMC Article
    5. Intracellular localization of GBF proteins and blue light-induced import of GBF2 fusion proteins into the nucleus of cultured Arabidopsis and soybean cells. Terzaghi WB, et al. Plant J, 1997 May. PMID 9193069

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    NM_001337182.1
    NM_001337183.1
    NM_130190.3
    NM_180118.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    G-box binding factor 3
    NP_182150.1
    • G-box binding factor 3 (GBF3); CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), G-box binding, MFMR (InterPro:IPR012900), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: G-box binding factor 2 (TAIR:AT4G01120.1); Has 2267 Blast hits to 2266 proteins in 215 species: Archae - 0; Bacteria - 77; Metazoa - 736; Fungi - 40; Plants - 1305; Viruses - 8; Other Eukaryotes - 101 (source: NCBI BLink).
    NP_850449.1
    • G-box binding factor 3 (GBF3); CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), G-box binding, MFMR (InterPro:IPR012900), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: G-box binding factor 2 (TAIR:AT4G01120.1); Has 2450 Blast hits to 2449 proteins in 240 species: Archae - 2; Bacteria - 73; Metazoa - 742; Fungi - 108; Plants - 1402; Viruses - 3; Other Eukaryotes - 120 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      19000180..19003403
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130190.3 → NP_182150.1  G-box binding factor 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42776
      UniProtKB/TrEMBL
      A0A178VVM5
      Conserved Domains (5) summary
      smart00338
      Location:257 → 320
      BRLZ; basic region leucin zipper
      cd14702
      Location:262 → 313
      bZIP_plant_GBF1; coiled coil [structural motif]
      pfam07777
      Location:1 → 96
      MFMR; G-box binding protein MFMR
      pfam16596
      Location:116 → 198
      MFMR_assoc; Disordered region downstream of MFMR
      cl19252
      Location:220 → 356
      MreC; rod shape-determining protein MreC

    2. NM_180118.2 → NP_850449.1  G-box binding factor 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VTX2, A0A5S9X7F5, F4II62
      Conserved Domains (3) summary
      smart00338
      Location:234 → 297
      BRLZ; basic region leucin zipper
      pfam07777
      Location:1 → 96
      MFMR; G-box binding protein MFMR
      pfam16596
      Location:129 → 197
      MFMR_assoc; Disordered region downstream of MFMR

    3. NM_001337182.1 → NP_001323457.1  G-box binding factor 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42776
      UniProtKB/TrEMBL
      A0A178VVM5

    4. NM_001337183.1 → NP_001323456.1  G-box binding factor 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VTX2, A0A5S9X7F5, F4II62
      Conserved Domains (3) summary
      smart00338
      Location:234 → 297
      BRLZ; basic region leucin zipper
      pfam07777
      Location:1 → 96
      MFMR; G-box binding protein MFMR
      pfam16596
      Location:129 → 197
      MFMR_assoc; Disordered region downstream of MFMR
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42776.2

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