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    Haus3 HAUS augmin-like complex, subunit 3 [ Mus musculus (house mouse) ]

    Gene ID: 231123, updated on 9-Dec-2024

    Summary

    Official Symbol
    Haus3provided by MGI
    Official Full Name
    HAUS augmin-like complex, subunit 3provided by MGI
    Primary source
    MGI:MGI:2387633
    See related
    Ensembl:ENSMUSG00000079555 AllianceGenome:MGI:2387633
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D4S43h; D5H4S43; D5H4S43E
    Summary
    Predicted to be involved in centrosome cycle and spindle assembly. Predicted to be located in centrosome and mitotic spindle microtubule. Predicted to be part of HAUS complex. Predicted to be active in microtubule organizing center and mitotic spindle. Is expressed in brain ventricular layer; paravertebral ganglion; renal cortex; and thymus primordium. Orthologous to human HAUS3 (HAUS augmin like complex subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E11.5 (RPKM 12.2), liver E14 (RPKM 7.4) and 14 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Haus3 in Genome Data Viewer
    Location:
    5 B2; 5 17.84 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (34311240..34326768, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (34153896..34169424, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene N-acetyltransferase 8-like Neighboring gene DNA polymerase N Neighboring gene STARR-seq mESC enhancer starr_12835 Neighboring gene RIKEN cDNA 4930557J02 gene Neighboring gene STARR-positive B cell enhancer ABC_E1299 Neighboring gene STARR-seq mESC enhancer starr_12836 Neighboring gene predicted gene, 25918 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:34530746-34530855 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:34537815-34537924 Neighboring gene Max dimerization protein 4 Neighboring gene zinc finger, FYVE domain containing 28 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:34575558-34575759 Neighboring gene cilia and flagella associated protein 99

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Clone Names

    • MGC36997, MGC38108, MGC38583

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in centrosome cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in centrosome cycle ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in microtubule organizing center organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spindle assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of HAUS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of HAUS complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of HAUS complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in mitotic spindle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitotic spindle microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitotic spindle microtubule ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    HAUS augmin-like complex subunit 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146159.2NP_666271.1  HAUS augmin-like complex subunit 3

      See identical proteins and their annotated locations for NP_666271.1

      Status: VALIDATED

      Source sequence(s)
      AC157989
      Consensus CDS
      CCDS19211.1
      UniProtKB/Swiss-Prot
      Q3TSW5, Q8BQL2, Q8CIH1, Q8QZX2
      Related
      ENSMUSP00000049973.7, ENSMUST00000060049.8
      Conserved Domains (1) summary
      pfam14932
      Location:29281
      HAUS-augmin3; HAUS augmin-like complex subunit 3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      34311240..34326768 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)