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    TIM10 protein transporter TIM10 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856395, updated on 2-Nov-2024

    Summary

    Official Symbol
    TIM10
    Official Full Name
    protein transporter TIM10
    Primary source
    SGD:S000003530
    Locus tag
    YHR005C-A
    See related
    AllianceGenome:SGD:S000003530; FungiDB:YHR005C-A; VEuPathDB:YHR005C-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MRS11
    Summary
    Enables protein transporter activity and unfolded protein binding activity. Involved in protein insertion into mitochondrial inner membrane. Located in mitochondrion. Part of mitochondrial intermembrane space protein transporter complex. Orthologous to human TIMM10 (translocase of inner mitochondrial membrane 10). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See TIM10 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (115620..115901, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Nem1-Spo7 phosphatase catalytic subunit NEM1 Neighboring gene guanine nucleotide-binding protein subunit alpha Neighboring gene tRNA-Thr Neighboring gene Stp2p

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables unfolded protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 

    General protein information

    Preferred Names
    protein transporter TIM10
    NP_011869.1
    • Essential protein of the mitochondrial intermembrane space; forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner membrane

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      115620..115901 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181427.1NP_011869.1  TPA: protein transporter TIM10 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011869.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKU9, P87108
      UniProtKB/TrEMBL
      A6ZSQ8, B3LSC4, C7GMQ7, C8ZA72, G2WF72, N1P523
      Conserved Domains (1) summary
      pfam02953
      Location:1880
      zf-Tim10_DDP; Tim10/DDP family zinc finger